Phenylalanine

Phenylalanine

SCHEMBL907512

CC(C)C[C@H](N)C(=O)O.CSCC[C@H](N)C(=O)O.N[C@@H](Cc1ccccc1)C(=O)O

nearest known ligand 0.58

Full drug profile on Sugi Atlas →

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
SLC7A5 Q01650 3/20 0.58
ALPI P09923 1/20 0.58
PKM P14618 1/20 0.58
PTGS1 P23219 1/20 0.58
XIAP P98170 1/20 0.58
ANPEP P15144 2/20 0.53
RNPEP Q9H4A4 2/20 0.53
DNPEP Q9ULA0 2/20 0.53
SLC1A3 P43003 1/20 0.51
SLC1A2 P43004 1/20 0.51
SLC1A1 P43005 1/20 0.51
LTA4H P09960 1/20 0.50
FNTA P49354 1/20 0.44
FNTB P49356 1/20 0.44
PGGT1B P53609 1/20 0.44
KMT2A Q03164 1/20 0.44
GRIK1 P39086 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
D-Phenylalanine SCHEMBL6450960 1.00 SLC7A5 (0.58) SLC7A5ALPIPKMPTGS1XIAP
Dl-Phenylalanine SCHEMBL29503517 0.92 SLC7A5 (0.69) SLC7A5ALPIPKMPTGS1XIAP
Dl-Phenylalanine SCHEMBL28076342 0.92 SLC7A5 (0.69) SLC7A5ALPIPKMPTGS1XIAP
Phenylalanine SCHEMBL464777 0.92 SLC7A5 (0.69) SLC7A5ALPIPKMPTGS1XIAP
Dl-Phenylalanine SCHEMBL464776 0.92 SLC7A5 (0.69) SLC7A5ALPIPKMPTGS1XIAP
Phenylalanine SCHEMBL28231547 0.92 SLC7A5 (0.69) SLC7A5ALPIPKMPTGS1XIAP
Phenylalanine SCHEMBL5503585 0.91 ALPI (0.48) SLC7A5ALPIPKMPTGS1XIAP
Phenylalanine SCHEMBL15323164 0.91 SLC7A5 (0.48) SLC7A5ALPIPKMPTGS1XIAP
Dl-Phenylalanine SCHEMBL6454258 0.91 SLC7A5 (0.48) SLC7A5ALPIPKMPTGS1XIAP
Phenylalanine SCHEMBL6454263 0.91 SLC7A5 (0.48) SLC7A5ALPIPKMPTGS1XIAP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1800692-B1 Immunological compositions and vaccines containing N-formyl methionyl peptide as adjuvant CONNAUGHT TECHNOLOGY CORP (US) 2011-01-26 EP claimed
EP-1800692-A1 Novel adjuvant for subunit or component vaccines Connaught Technology Corporation (US) 2007-06-27 EP claimed
WO-2006049599-A1 METHODS OF DETECTION AND THERAPY FOR ATHEROMATOUS PLAQUES USING IMMUNE MODULATION THE GENERAL HOSPITAL CORPORATION (US) 2006-05-11 WO claimed
EP-1140166-A2 NOVEL ADJUVANT FOR SUBUNIT OR COMPONENT VACCINES VIROGENETICS CORPORATION (US) 2001-10-10 EP claimed
WO-2000035482-A2 NOVEL ADJUVANT FOR SUBUNIT OR COMPONENT VACCINES VIROGENETICS CORPORATION (US) 2000-06-22 WO claimed
US-20240226211-A9 SEAWEED EXTRACTS, ISOLATED COMPOUNDS, AND METHODS OF TREATMENT UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) 2024-07-11 US disclosed
US-20240131097-A1 SEAWEED EXTRACTS, ISOLATED COMPOUNDS, AND METHODS OF TREATMENT UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) 2024-04-25 US disclosed
CN-116731181-B Anti-human CD10 protein rabbit monoclonal antibody and application thereof 武汉爱博泰克生物科技有限公司 2024-01-12 CN disclosed
WO-2023230593-A1 PTP1B INHIBITORS FOR TREATING LUNG INJURY COLD SPRING HARBOR LABORATORY (US) 2023-11-30 WO disclosed
CN-116731181-A Anti-human CD10 protein rabbit monoclonal antibody and application thereof 武汉爱博泰克生物科技有限公司 2023-09-12 CN disclosed
US-20220047698-A1 SYNTHETIC INNATE IMMUNE RECEPTOR LIGANDS AND USES THEREOF ALBERTA RES CHEMICALS INC (CA) 2022-02-17 US disclosed
US-20210161980-A1 SEAWEED EXTRACTS, ISOLATED COMPOUNDS, AND METHODS OF TREATMENT NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2021-06-03 US disclosed
US-5595737-A Methods for using monoclonal antibodies specific for cell-surface bound LAM-1 DANA-FARBER CANCER INSTITUTE, INC. (US) 1997-01-21 US disclosed
EP-0633785-A4 SPECIFIC DETECTION OF CELL SURFACE RECEPTOR LEUKOCYTE ADHESION MOLECULE-1. DANA FARBER CANCER INST INC (US) 1995-04-05 EP disclosed
US-5389520-A Specific detection of cell surface receptor leukocyte adhesion molecule-1 DANA-FARBER CANCER INSTITUTE, INC. (US) 1995-02-14 US disclosed
EP-0633785-A1 SPECIFIC DETECTION OF CELL SURFACE RECEPTOR LEUKOCYTE ADHESION MOLECULE-1 DANA-FARBER CANCER INSTITUTE, INC. (US) 1995-01-18 EP disclosed
WO-1993019782-A1 SPECIFIC DETECTION OF CELL SURFACE RECEPTOR LEUKOCYTE ADHESION MOLECULE-1 DANA-FARBER CANCER INSTITUTE, INC. (US) 1993-10-14 WO disclosed
EP-0463116-A4 IMAGING TISSUE SITES OF INFLAMMATION 1992-02-19 EP disclosed
EP-0463116-A1 IMAGING TISSUE SITES OF INFLAMMATION NEORX CORPORATION (US) 1992-01-02 EP disclosed
WO-1990010463-A1 IMAGING TISSUE SITES OF INFLAMMATION NEORX CORPORATION (US) 1990-09-20 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240131097-A1 SEAWEED EXTRACTS, ISOLATED COMPOUNDS, AND METHODS OF TREATMENT KEAP1, NFE2L2, TFEB SLC7A5 4010/4885ALPI 4037/4885PKM 3213/4885
US-20210161980-A1 SEAWEED EXTRACTS, ISOLATED COMPOUNDS, AND METHODS OF TREATMENT KEAP1, NFE2L2, TFEB SLC7A5 4010/4885ALPI 4037/4885PKM 3213/4885
US-20240226211-A9 SEAWEED EXTRACTS, ISOLATED COMPOUNDS, AND METHODS OF TREATMENT KEAP1, NFE2L2, TFEB SLC7A5 4010/4885ALPI 4037/4885PKM 3213/4885
US-20220047698-A1 SYNTHETIC INNATE IMMUNE RECEPTOR LIGANDS AND USES THEREOF TLR3, TLR4, TLR9 SLC7A5 2711/4885ALPI 2378/4885PKM 1332/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.