Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.48 |
| ▸ | RAB9A | P51151 | 8/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.48 |
| ▸ | NPC1 | O15118 | 6/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.48 |
| ▸ | HPGD | P15428 | 5/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8837925 | 0.84 | KDM4E (0.48) | ALDH1A1RAB9AKDM4ENPC1HSD17B10 | |
| SCHEMBL8305023 | 0.78 | ALDH1A1 (0.44) | ALDH1A1RAB9AKDM4EHSD17B10HPGD | |
| SCHEMBL8554638 | 0.73 | ALDH1A1 (0.40) | ALDH1A1RAB9AKDM4ENPC1HSD17B10 | |
| SCHEMBL8324883 | 0.72 | NPC1 (0.48) | ALDH1A1RAB9AKDM4ENPC1HSD17B10 | |
| SCHEMBL8307013 | 0.72 | ALDH1A1 (0.45) | ALDH1A1KDM4EHSD17B10HPGDMAPT | |
| SCHEMBL8837860 | 0.71 | KDM4E (0.52) | ALDH1A1KDM4EHSD17B10HPGDGLA | |
| SCHEMBL8326272 | 0.71 | CA12 (0.41) | ALDH1A1RAB9AKDM4EHSD17B10HPGD | |
| SCHEMBL8305025 | 0.70 | ALDH1A1 (0.41) | ALDH1A1RAB9AKDM4ENPC1HSD17B10 | |
| SCHEMBL8553130 | 0.70 | ALDH1A1 (0.38) | ALDH1A1RAB9AKDM4ENPC1HSD17B10 | |
| SCHEMBL16547892 | 0.69 | MAPT (0.57) | ALDH1A1RAB9AKDM4ENPC1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5565488-A | ANTIINFLAMMATORY AGENTS | BAYER AKTIENGESELLSCHAFT (DE) | 1996-10-15 | — | — | US | claimed |