Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 8/20 | 0.72 |
| ▸ | PDE4B | Q07343 | 7/20 | 0.72 |
| ▸ | PDE4C | Q08493 | 7/20 | 0.72 |
| ▸ | PDE4D | Q08499 | 7/20 | 0.72 |
| ▸ | FEN1 | P39748 | 1/20 | 0.43 |
| ▸ | PDE1A | P54750 | 1/20 | 0.42 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | LOXL3 | P58215 | 1/20 | 0.42 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | LDHA | P00338 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | PRNP | P04156 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7271411 | 0.84 | PDE4A (1.00) | PDE4APDE4BPDE4CPDE4DFEN1 | |
| SCHEMBL2457079 | 0.78 | PDE4A (0.81) | PDE4APDE4BPDE4CPDE4DFEN1 | |
| SCHEMBL7280371 | 0.73 | PDE4A (0.79) | PDE4APDE4BPDE4CPDE4DFEN1 | |
| SCHEMBL9079411 | 0.72 | PDE4A (0.73) | PDE4APDE4BPDE4CPDE4DFEN1 | |
| SCHEMBL7273701 | 0.71 | PDE4A (0.76) | PDE4APDE4BPDE4CPDE4DFEN1 | |
| SCHEMBL7279657 | 0.70 | PDE4A (0.74) | PDE4APDE4BPDE4CPDE4DFEN1 | |
| SCHEMBL7340105 | 0.70 | PDE4A (0.74) | PDE4APDE4BPDE4CPDE4DPDE1A | |
| SCHEMBL2294487 | 0.69 | PDE4A (0.51) | PDE4APDE4BPDE4CPDE4DALDH1A1 | |
| SCHEMBL7328426 | 0.69 | PDE4A (0.71) | PDE4APDE4BPDE4CPDE4DALDH1A1 | |
| SCHEMBL9076980 | 0.69 | PDE4A (0.75) | PDE4APDE4BPDE4CPDE4DFEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5484924-A | ANTIALLERGEN, ANTIINFLAMMATORY, ANTIASTHMA | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1996-01-16 | — | — | US | disclosed |
| EP-0614897-A1 | IMIDAZONAPHTHYRIDINE DERIVATIVE | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1994-09-14 | — | — | EP | disclosed |