Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LDHA | P00338 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | MMP1 | P03956 | 3/20 | 0.46 |
| ▸ | MMP13 | P45452 | 3/20 | 0.46 |
| ▸ | IDO1 | P14902 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | CTBP2 | P56545 | 1/20 | 0.45 |
| ▸ | F2RL1 | P55085 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | MMP9 | P14780 | 2/20 | 0.44 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | PPARA | Q07869 | 1/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28136422 | 0.82 | LDHA (0.53) | LDHAHTTMMP1MMP13NPC1 | |
| SCHEMBL3801397 | 0.82 | LDHA (0.53) | LDHAHTTMMP1MMP13NPC1 | |
| SCHEMBL3739737 | 0.81 | LDHA (0.51) | LDHAHTTMMP1MMP13NPC1 | |
| SCHEMBL4413232 | 0.81 | LDHA (0.51) | LDHAHTTMMP1MMP13NPC1 | |
| SCHEMBL28246723 | 0.81 | LDHA (0.51) | LDHAHTTMMP1MMP13NPC1 | |
| SCHEMBL7676911 | 0.81 | LDHA (0.51) | LDHAHTTMMP1MMP13NPC1 | |
| SCHEMBL7716562 | 0.80 | BLM (0.44) | IDO1NPC1RAB9APOLBSMN1; SMN2 | |
| SCHEMBL5208103 | 0.80 | LDHA (0.55) | LDHAHTTNPC1RAB9APOLB | |
| SCHEMBL3342965 | 0.80 | SMN1; SMN2 (0.53) | SMN1; SMN2PPARGPPARA | |
| SCHEMBL1424653 | 0.79 | BLM (0.67) | LDHAHTTMMP1MMP13NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0710243-A1 | IMPROVED SYNTHESIS OF CYCLIC PEPTIDES | FERRING B.V. (NL) | 1996-05-08 | — | — | EP | disclosed |
| WO-1995001368-A1 | IMPROVED SYNTHESIS OF CYCLIC PEPTIDES | FERRING B.V. (NL) | 1995-01-12 | — | — | WO | disclosed |