Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | USP2 | O75604 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.46 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL196635 | 0.88 | KMT2A (0.49) | ALDH1A1KDM4EUSP2HTTTSHR | |
| Hydrochloric Acid SCHEMBL2238154 | 0.86 | KMT2A (0.47) | ALDH1A1HTTTSHRSMN1; SMN2RAB9A | |
| Ethane SCHEMBL7405342 | 0.86 | KMT2A (0.47) | ALDH1A1HTTTSHRSMN1; SMN2RAB9A | |
| SCHEMBL11973371 | 0.86 | KMT2A (0.47) | ALDH1A1HTTTSHRSMN1; SMN2RAB9A | |
| SCHEMBL11973878 | 0.86 | KMT2A (0.47) | ALDH1A1HTTTSHRSMN1; SMN2RAB9A | |
| SCHEMBL9456006 | 0.84 | FFAR1 (0.46) | ALDH1A1KDM4EUSP2SLC6A9FFAR1 | |
| SCHEMBL28709069 | 0.82 | ALDH1A1 (0.47) | ALDH1A1KDM4EUSP2TSHRMAPT | |
| SCHEMBL20120105 | 0.82 | ALDH1A1 (0.48) | ALDH1A1KDM4EUSP2MAPTAGTR1 | |
| SCHEMBL3348892 | 0.80 | KEAP1 (0.54) | ALDH1A1GAATSHRSMN1; SMN2RAB9A | |
| SCHEMBL13644999 | 0.80 | LMNA (0.50) | ALDH1A1KDM4EUSP2LMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080227858-A1 | Inhibitors of matrix metalloproteinase | GLAXO GROUP LIMITED | 2008-09-18 | — | — | US | disclosed |
| US-7375248-B2 | Inhibitors of matrix metalloproteinase | GLAXO GROUP LIMITED (GB) | 2008-05-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080227858-A1 | Inhibitors of matrix metalloproteinase | MMP9, MMP13, MMP2 | ALDH1A1 3221/4885KDM4E 1307/4885USP2 2649/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.