Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | ACACB | O00763 | 1/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | PDE2A | O00408 | 1/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.32 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.32 |
| ▸ | DHFR | P00374 | 1/20 | 0.32 |
| ▸ | DCPS | Q96C86 | 1/20 | 0.32 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.32 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.32 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.32 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.31 |
| ▸ | RET | P07949 | 1/20 | 0.31 |
| ▸ | LTA4H | P09960 | 1/20 | 0.31 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.30 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9080688 | 0.91 | TDP1 (0.38) | HTR1ATDP1KCNA3GRM2ADRA1A | |
| SCHEMBL3048952 | 0.81 | ACACB (0.44) | HTR1AACACBFFAR1PDE2APDE10A | |
| SCHEMBL2850237 | 0.81 | KCNA3 (0.43) | HTR1ATDP1KCNA3LTA4HADRA1A | |
| SCHEMBL36030 | 0.78 | MEN1 (0.41) | HTR1ATDP1KCNA3LTA4HLMNA | |
| SCHEMBL1714455 | 0.74 | ALDH1A1 (0.42) | TDP1KCNA3 | |
| SCHEMBL13301302 | 0.73 | LTA4H (0.51) | LTA4H | |
| SCHEMBL16689102 | 0.72 | PDE9A (0.39) | HTR1ATDP1KCNA3ADRA1A | |
| SCHEMBL3473044 | 0.72 | LTA4H (0.45) | HTR1AKCNA3LTA4HDRD2LMNA | |
| SCHEMBL9935890 | 0.71 | ACACB (0.50) | ACACBFFAR1PDE2APDE10ASLC5A1 | |
| SCHEMBL17899755 | 0.70 | KCNA3 (0.50) | HTR1AKCNA3LTA4HDRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5523424-A | REACTING A 3,3-BIS(TOSYL-, MESYLYL- OR HALOMETHYL)OXETANE AND A METAL AZIDE IN AN AQUEOUS SOLUTION CONTAINING A PHASE TRANSFER CATALYST | AEROJET-GENERAL CORPORATION (US) | 1996-06-04 | — | — | US | disclosed |