Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 4/20 | 0.37 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 4/20 | 0.34 |
| ▸ | ADRA1D | P25100 | 3/20 | 0.33 |
| ▸ | ADRA1B | P35368 | 3/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9080366 | 0.91 | HTR1A (0.35) | TDP1KCNA3HTR1AGRM2ADRA1A | |
| SCHEMBL2850237 | 0.89 | KCNA3 (0.43) | TDP1KCNA3HTR1AALDH1A1TAAR1 | |
| SCHEMBL1714455 | 0.82 | ALDH1A1 (0.42) | TDP1KCNA3ALDH1A1RECQLALOX15 | |
| SCHEMBL36030 | 0.82 | MEN1 (0.41) | TDP1KCNA3HTR1A | |
| SCHEMBL16689102 | 0.79 | PDE9A (0.39) | TDP1KCNA3HTR1AALDH1A1TAAR1 | |
| SCHEMBL13301302 | 0.77 | LTA4H (0.51) | — | |
| SCHEMBL5945052 | 0.76 | PARP10 (0.41) | ALOX15 | |
| SCHEMBL3473044 | 0.76 | LTA4H (0.45) | KCNA3HTR1AALDH1A1 | |
| SCHEMBL11013902 | 0.76 | ALDH1A1 (0.42) | TDP1KCNA3HTR1AALDH1A1TAAR1 | |
| SCHEMBL3515342 | 0.74 | TAAR1 (0.41) | TDP1KCNA3HTR1AALDH1A1TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5523424-A | REACTING A 3,3-BIS(TOSYL-, MESYLYL- OR HALOMETHYL)OXETANE AND A METAL AZIDE IN AN AQUEOUS SOLUTION CONTAINING A PHASE TRANSFER CATALYST | AEROJET-GENERAL CORPORATION (US) | 1996-06-04 | — | — | US | disclosed |