Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | CYP46A1 | Q9Y6A2 | 1/20 | 0.32 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.32 |
| ▸ | HSD11B2 | P80365 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.30 |
| ▸ | FABP3 | P05413 | 1/20 | 0.30 |
| ▸ | FABP4 | P15090 | 1/20 | 0.30 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9279045 | 0.94 | MCL1 (0.38) | NPSR1ALDH1A1TSHRLMNAKDM4E | |
| SCHEMBL9077919 | 0.92 | AHR (0.34) | MAPTCYP46A1KDM4EKMT2A | |
| SCHEMBL9079251 | 0.89 | NPSR1 (0.34) | NPSR1ALDH1A1MAPTTSHRCYP46A1 | |
| SCHEMBL9079247 | 0.79 | NR4A2 (0.39) | NR4A2LMNAKDM4ESMN1; SMN2 | |
| SCHEMBL9078562 | 0.75 | KDM4E (0.35) | NPSR1ALDH1A1MAPTTSHRNR4A2 | |
| SCHEMBL9277713 | 0.74 | NR4A2 (0.38) | ALDH1A1NR4A2LMNAKDM4EMCL1 | |
| SCHEMBL9080914 | 0.73 | KDM4E (0.39) | NPSR1ALDH1A1MAPTTSHRLMNA | |
| SCHEMBL9079782 | 0.73 | MTNR1B (0.35) | NPSR1ALDH1A1MAPTTSHRNR4A2 | |
| SCHEMBL9257773 | 0.72 | ADORA2B (0.37) | ALDH1A1MAPTTSHRNR4A2LMNA | |
| SCHEMBL9079825 | 0.71 | GABRA1 (0.48) | MAPTCYP46A1LMNAKDM4EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5512590-A | PREVENTS DISORDER OF GABAERGIC TRANSMISSION | SYNTHELABO (FR) | 1996-04-30 | — | — | US | disclosed |
| EP-0682025-A1 | 5,6-dihydro-4H-imidazo 2',1':2,3 imidazo 4,5,1-ij quinoline and 4,5-dihydroimidazo 1,2-a pyrrolo 1,2,3-cd benzimidazol derivatives | SYNTHELABO (FR) | 1995-11-15 | — | — | EP | disclosed |