Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2B | P29275 | 1/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.37 |
| ▸ | FAAH | O00519 | 1/20 | 0.35 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.35 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.34 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.34 |
| ▸ | PDE1A | P54750 | 1/20 | 0.33 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.33 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | FABP3 | P05413 | 1/20 | 0.32 |
| ▸ | FABP4 | P15090 | 1/20 | 0.32 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9257774 | 0.89 | ADORA3 (0.43) | ADORA2BADORA1FAAHNR4A2KDM4E | |
| SCHEMBL9261214 | 0.86 | ADORA2B (0.41) | ADORA2BADORA1MAPTHPGDKDM4E | |
| SCHEMBL9263544 | 0.86 | HPGD (0.40) | ADORA2BADORA1MAPTHPGDKDM4E | |
| SCHEMBL9258312 | 0.83 | ADORA1 (0.38) | ADORA2BADORA1HPGDKDM4EALDH1A1 | |
| SCHEMBL9264420 | 0.79 | CXCR3 (0.39) | ADORA1MAPTHPGDKDM4EALDH1A1 | |
| SCHEMBL9258447 | 0.77 | NR4A2 (0.43) | ADORA2BADORA1FAAHNR4A2HPGD | |
| SCHEMBL9258551 | 0.72 | TRPM2 (0.37) | FAAHMAPTSMN1; SMN2HPGDKDM4E | |
| SCHEMBL9080373 | 0.72 | NPSR1 (0.34) | NR4A2MAPTFABP3FABP4FABP5 | |
| SCHEMBL9416617 | 0.72 | ADORA1 (0.39) | ADORA2BADORA1HPGDKDM4EALDH1A1 | |
| SCHEMBL9260636 | 0.71 | KDM4E (0.39) | ADORA2BADORA1FAAHNR4A2PDE1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5466706-A | Compounds for hypnotics, anxiety or anticonvulsants | SYNTHELABO (FR) | 1995-11-14 | — | — | US | disclosed |
| EP-0607076-A1 | 9H-Imidazo 1,2-a benzimidazole derivatives with GABA activity | SYNTHELABO (FR) | 1994-07-20 | — | — | EP | disclosed |