Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JUN | P05412 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.44 |
| ▸ | NCF1 | P14598 | 1/20 | 0.44 |
| ▸ | PLD1 | Q13393 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.40 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.39 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.38 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.38 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.37 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.37 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.37 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11472515 | 0.85 | JUN (0.58) | JUNNFKB1POLBHPGDMEN1 | |
| SCHEMBL11472516 | 0.85 | JUN (0.58) | JUNNFKB1POLBHPGDMEN1 | |
| SCHEMBL7827702 | 0.83 | SIGMAR1 (0.56) | SIGMAR1POLBRXFP1MEN1KMT2A | |
| SCHEMBL5273 | 0.75 | SIGMAR1 (0.70) | ADRB2NCF1PLD1SIGMAR1MKNK1 | |
| Hydrochloric Acid SCHEMBL1597605 | 0.74 | SIGMAR1 (0.68) | SIGMAR1MKNK1MKNK2CHRNB2CHRNB4 | |
| SCHEMBL27667265 | 0.72 | ME2 (0.53) | POLBMEN1KMT2A | |
| SCHEMBL4210727 | 0.71 | KMT2A (0.63) | JUNNFKB1POLBHPGDMEN1 | |
| SCHEMBL4210731 | 0.71 | KMT2A (0.63) | JUNNFKB1POLBHPGDMEN1 | |
| SCHEMBL293023 | 0.71 | FNTA (0.57) | ADRB2NCF1PLD1TPSAB1TPSD1 | |
| SCHEMBL11470275 | 0.71 | RAB9A (0.62) | JUNNFKB1MKNK1MKNK2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996034866-A1 | IMIDAZO 1,2-A PYRIDINE AND IMIDAZO 1,2-A PYRIDEZINE DERIVATIVES AND THEIR USE AS BONE RESORPTION INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-11-07 | — | — | WO | disclosed |