Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | PKM | P14618 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | CRHBP | P24387 | 1/20 | 0.44 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.44 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.43 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.43 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.43 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.43 |
| ▸ | TTR | P02766 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9081516 | 0.88 | KMT2A (0.48) | GPR35KMT2AALDH1A1MAPTPKM | |
| SCHEMBL259511 | 0.88 | CASP6 (0.53) | KMT2AALDH1A1MAPTPKMRAB9A | |
| Hydrochloric Acid SCHEMBL1142710 | 0.87 | KMT2A (0.47) | GPR35KMT2AALDH1A1MAPTPKM | |
| SCHEMBL460048 | 0.85 | CA12 (0.64) | KMT2AALDH1A1MAPTPKMRAB9A | |
| SCHEMBL12229762 | 0.83 | TSHR (0.59) | KMT2AALDH1A1MAPTPKMRAB9A | |
| SCHEMBL12870183 | 0.83 | GPR35 (0.43) | GPR35KMT2AALDH1A1MAPTPKM | |
| SCHEMBL13568500 | 0.81 | GPR35 (0.44) | GPR35KMT2AALDH1A1MAPTPKM | |
| SCHEMBL4413302 | 0.81 | VCAM1 (0.58) | ALDH1A1MAPTPKMNPC1LMNA | |
| SCHEMBL1827529 | 0.81 | LMNA (0.56) | KMT2AALDH1A1MAPTPKMRAB9A | |
| Hydrochloric Acid SCHEMBL1552568 | 0.79 | LMNA (0.55) | KMT2AALDH1A1MAPTPKMRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996028443-A1 | THERAPEUTIC BENZOXAZOLES | THE WELLCOME FOUNDATION LIMITED (GB) | 1996-09-19 | — | — | WO | disclosed |