Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 6/20 | 0.39 |
| ▸ | KDM1A | O60341 | 3/20 | 0.39 |
| ▸ | MAOA | P21397 | 3/20 | 0.35 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.34 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
| ▸ | NOS3 | P29474 | 2/20 | 0.33 |
| ▸ | NOS1 | P29475 | 2/20 | 0.33 |
| ▸ | NOS2 | P35228 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1726141 | 0.71 | KDM1A (0.39) | KDM1AMAOAMAOB | |
| SCHEMBL1153469 | 0.67 | KDM1A (0.44) | KDM1AMAOAMAOB | |
| SCHEMBL4329271 | 0.67 | MAOA (0.46) | KDM1AMAOAPARP10TSHRLMNA | |
| SCHEMBL734440 | 0.66 | KDM1A (0.38) | KDM1AMAOAMAOB | |
| SCHEMBL11513408 | 0.66 | PARP10 (0.37) | LTA4HPARP10FFAR1 | |
| SCHEMBL31294912 | 0.65 | HPGD (0.39) | LTA4HMAOATSHRLMNAHTT | |
| SCHEMBL29033525 | 0.64 | KDM1A (0.34) | KDM1AMAOAMAOB | |
| SCHEMBL29806042 | 0.63 | — | — | |
| Diphenylether SCHEMBL27626785 | 0.63 | LTA4H (0.67) | LTA4HMAOAPLA2G2ANOS3NOS1 | |
| Diphenylether SCHEMBL296590 | 0.62 | LTA4H (0.75) | LTA4HMAOAPLA2G2ATSHRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996034851-A1 | BENZENE, PYRIDINE, NAPHTALENE OR BENZOPHENONE DERIVATIVES AS INHIBITORS OF SQUALENE SYNTHETASE AND PROTEIN FARNESYLTRANSFERASE | ABBOTT LABORATORIES (US) | 1996-11-07 | — | — | WO | disclosed |