Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 10/20 | 0.39 |
| ▸ | MAOA | P21397 | 10/20 | 0.39 |
| ▸ | MAOB | P27338 | 10/20 | 0.39 |
| ▸ | MMP2 | P08253 | 3/20 | 0.33 |
| ▸ | MMP9 | P14780 | 3/20 | 0.33 |
| ▸ | MMP3 | P08254 | 1/20 | 0.33 |
| ▸ | MMP8 | P22894 | 2/20 | 0.32 |
| ▸ | MMP13 | P45452 | 2/20 | 0.32 |
| ▸ | SLC10A2 | Q12908 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3458780 | 0.74 | KCNH2 (0.39) | MMP2MMP9MMP3 | |
| SCHEMBL1153469 | 0.72 | KDM1A (0.44) | KDM1AMAOAMAOB | |
| SCHEMBL734440 | 0.71 | KDM1A (0.38) | KDM1AMAOAMAOB | |
| SCHEMBL9080707 | 0.71 | LTA4H (0.39) | KDM1AMAOAMAOB | |
| SCHEMBL3102574 | 0.71 | POLA1 (0.35) | — | |
| SCHEMBL10674140 | 0.71 | KDM1A (0.38) | KDM1AMAOAMAOB | |
| SCHEMBL9423932 | 0.69 | POLA1 (0.30) | — | |
| SCHEMBL10335526 | 0.69 | GAA (0.32) | KDM1AMAOAMAOBMMP2MMP9 | |
| SCHEMBL5149443 | 0.67 | HTR2A (0.39) | KDM1AMAOAMAOB | |
| SCHEMBL9100196 | 0.67 | KDM1A (0.34) | KDM1AMAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2406210-A1 | PROCESS FOR PREPARING SUBSTITUTED 2-NITROBIPHENYLS | BASF SE (DE) | 2012-01-18 | — | — | EP | claimed |
| WO-2010102980-A1 | PROCESS FOR PREPARING SUBSTITUTED 2-NITROBIPHENYLS | BASF SE (DE) | 2010-09-16 | — | — | WO | claimed |
| US-8853455-B2 | Process for preparing substituted 2-nitrobiphenyls | BASF SE (DE) | 2014-10-07 | — | — | US | disclosed |
| US-8637707-B2 | Method for producing aminobiphenylene | BASF SE (DE) | 2014-01-28 | — | — | US | disclosed |
| EP-2406210-A1 | PROCESS FOR PREPARING SUBSTITUTED 2-NITROBIPHENYLS | BASF SE (DE) | 2012-01-18 | — | — | EP | disclosed |
| US-20110319665-A1 | Process for Preparing Substituted 2-Nitrobiphenyls | BASF SE (DE) | 2011-12-29 | — | — | US | disclosed |
| WO-2010102980-A1 | PROCESS FOR PREPARING SUBSTITUTED 2-NITROBIPHENYLS | BASF SE (DE) | 2010-09-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110319665-A1 | Process for Preparing Substituted 2-Nitrobiphenyls | CYP2J2, LTC4S, CYP1A2 | KDM1A 1337/4885MAOA 301/4885MAOB 88/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.