SCHEMBL4329271

SCHEMBL4329271

Nc1ccc(Oc2ccc(C3(c4ccc(Oc5ccc(N)cc5)cc4)C=CC=CC3c3ccccc3)cc2)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 2/20 0.46
MEN1 O00255 4/20 0.40
KMT2A Q03164 4/20 0.40
NPC1 O15118 3/20 0.40
RAB9A P51151 3/20 0.40
NLRP3 Q96P20 1/20 0.40
ALDH1A1 P00352 7/20 0.39
TDP1 Q9NUW8 2/20 0.39
CYP3A4 P08684 1/20 0.39
TSHR P16473 1/20 0.39
NCOA1 Q15788 1/20 0.38
NCOA3 Q9Y6Q9 1/20 0.38
MAPT P10636 6/20 0.37
SMN1; SMN2 Q16637 3/20 0.37
MITF O75030 1/20 0.37
GAA P10253 1/20 0.37
GFER P55789 1/20 0.37
NLRP1 Q9C000 1/20 0.37
NOD2 Q9HC29 1/20 0.37
MAOB P27338 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6067732 0.75 MAOA (0.38) MAOAMEN1KMT2ANPC1RAB9A
SCHEMBL6750483 0.72 MAOA (0.50) MAOAMEN1KMT2ANPC1RAB9A
SCHEMBL14119070 0.70 MAPT (0.39) MAOANPC1ALDH1A1CYP3A4MAPT
SCHEMBL31174259 0.68 KDM4E (0.32) MAOAMEN1KMT2ATDP1CYP3A4
4-Phenoxyaniline SCHEMBL159084 0.67 MAOA (1.00) MAOAMEN1KMT2ANPC1RAB9A
Diphenylether SCHEMBL28089995 0.67 MAOA (1.00) MAOAMEN1KMT2ANPC1RAB9A
SCHEMBL554324 0.67 MAOA (1.00) MAOAMEN1KMT2ANPC1RAB9A
SCHEMBL9080707 0.67 LTA4H (0.39) MAOATSHRMAOBPARP10KDM1A
Benzene SCHEMBL28182432 0.67 MAOA (0.89) MAOAMEN1KMT2ANPC1RAB9A
SCHEMBL734440 0.66 KDM1A (0.38) MAOAMAOBKDM1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7615260-B2 Active-matrix liquid crystal display HITACHI, LTD. (JP) 2009-11-10 US disclosed
US-20050012884-A1 Active-matrix liquid crystal display IPS ALPHA SUPPORT CO., LTD. (JP) 2005-01-20 US disclosed
EP-0806698-B1 In-plane switching-mode active-matrix liquid crystal display HITACHI LTD (JP) 2005-01-12 EP disclosed
US-6756089-B2 MULTILAYER; POLYAMIDEIMIDE COPOLYMER HITACHI, LTD. (JP) 2004-06-29 US disclosed
US-20010046569-A1 Active-matrix liquid crystal display IPS ALPHA SUPPORT CO., LTD. (JP) 2001-11-29 US disclosed
US-6242060-B1 MULTILAYER HITACHI, LTD. (JP) 2001-06-05 US disclosed
EP-0806698-A1 Active-matrix liquid crystal display HITACHI, LTD. (JP) 1997-11-12 EP disclosed