Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 2/20 | 0.34 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.34 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.34 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.34 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.34 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.34 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.34 |
| ▸ | AR | P10275 | 2/20 | 0.34 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.34 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.34 |
| ▸ | EGLN2 | Q96KS0 | 5/20 | 0.32 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.31 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6319050 | 0.79 | KMO (0.43) | EGLN2 | |
| SCHEMBL9081521 | 0.77 | BACE1 (0.33) | GABRA1GABRA5GABRA2GABRB2GABRA3 | |
| SCHEMBL8474290 | 0.77 | ERN1 (0.41) | — | |
| SCHEMBL4507194 | 0.76 | STIM1 (0.44) | — | |
| SCHEMBL9080670 | 0.73 | MAPT (0.43) | GABRA1GABRA5GABRA2GABRB2GABRA3 | |
| SCHEMBL8444200 | 0.72 | TRPV4 (0.39) | AREGLN2CYP11B1CYP11B2 | |
| SCHEMBL17290382 | 0.70 | HSD11B1 (0.46) | — | |
| SCHEMBL22756712 | 0.68 | PDK1 (0.40) | GABRA5GABRA3PDK1PDK2EGLN2 | |
| SCHEMBL16664821 | 0.67 | HSD11B1 (0.44) | — | |
| SCHEMBL14307269 | 0.66 | ESR1 (0.44) | MAP2K2MAP2K1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996015115-A1 | HERBICIDAL PYRAZOLE COMPOUNDS | ZENECA LIMITED (GB) | 1996-05-23 | — | — | WO | disclosed |