Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMO | O15229 | 2/20 | 0.43 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.40 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.37 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.37 |
| ▸ | PDE2A | O00408 | 2/20 | 0.36 |
| ▸ | GRM2 | Q14416 | 6/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | BCHE | P06276 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.33 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7707702 | 0.84 | KMO (0.42) | KMOHSD11B1GRIN2BEGLN2PDE2A | |
| SCHEMBL4032763 | 0.84 | HSD11B1 (0.49) | HSD11B1 | |
| SCHEMBL12297649 | 0.83 | HSD11B1 (0.40) | HSD11B1GRM2IDO1PDE4APDE4B | |
| SCHEMBL9081963 | 0.81 | KMO (0.40) | KMOHSD11B1GRIN2BEGLN2PDE2A | |
| SCHEMBL8474290 | 0.79 | ERN1 (0.41) | PDE2AGRM2CYP2C9 | |
| SCHEMBL9080977 | 0.79 | GABRA1 (0.34) | EGLN2 | |
| SCHEMBL7508249 | 0.79 | KMO (0.39) | KMOHSD11B1GRIN2BEGLN2PDE2A | |
| SCHEMBL4507194 | 0.79 | STIM1 (0.44) | IDO1 | |
| SCHEMBL17290382 | 0.78 | HSD11B1 (0.46) | HSD11B1PDE2AGRM2 | |
| SCHEMBL7475083 | 0.76 | CA12 (0.48) | KMOGRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6897322-B2 | Method of producing 1-alkyl-3-aryl-5-difluoromethoxy-1H-pyrazoles | BASF AKTIENGESELLSCHAFT (DE) | 2005-05-24 | — | — | US | disclosed |
| US-20040059128-A1 | Method of producing 1-alkyl-3-aryl-5-difluoromethoxy-ih-pyrazoles | BASF AKTIENGESELLSCHAFT (DE) | 2004-03-25 | — | — | US | disclosed |
| US-H1942-H1 | MADE BY REACTING 1-METHYL-5-DIFLUOROMETHOXY-4-CHLORO-3-(2-FLUORO-4-CHLORO-5 -AMINOPHENYL)PYRAZOLE WITH T-BUTYL NITRITE, COPPER CHLORIDE, AND ETHYL ACRYLATE IN ACETONITRILE, FOR EXAMPLE | FMC CORPORATION | 2001-02-06 | — | — | US | disclosed |
| WO-1996015115-A1 | HERBICIDAL PYRAZOLE COMPOUNDS | ZENECA LIMITED (GB) | 1996-05-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040059128-A1 | Method of producing 1-alkyl-3-aryl-5-difluoromethoxy-ih-pyrazoles | CYP2E1, CYP2F1, CYP1A1 | KMO 127/4885HSD11B1 77/4885GRIN2B 3143/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.