Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | CASR | P41180 | 5/20 | 0.42 |
| ▸ | TERT | O14746 | 1/20 | 0.39 |
| ▸ | GRM4 | Q14833 | 5/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | NR1I3 | Q14994 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6959466 | 0.84 | CASR (0.45) | POLBLMNACASREPHX2TSHR | |
| SCHEMBL6951008 | 0.80 | HRH3 (0.41) | EPHX2ALDH1A1 | |
| SCHEMBL3505067 | 0.79 | ACHE (0.40) | LMNAGRM4EPHX2ALDH1A1HPGD | |
| SCHEMBL3508760 | 0.78 | HTR2A (0.39) | CASRALDH1A1 | |
| SCHEMBL8947062 | 0.78 | ACHE (0.42) | LMNAALDH1A1HPGD | |
| SCHEMBL3504376 | 0.77 | GRM4 (0.41) | LMNAGRM4TSHRALDH1A1HPGD | |
| SCHEMBL3505500 | 0.76 | ALDH1A1 (0.43) | TSHRALDH1A1 | |
| SCHEMBL3505169 | 0.75 | CASR (0.42) | CASRALDH1A1 | |
| SCHEMBL6956988 | 0.74 | ACHE (0.47) | POLBALDH1A1HTT | |
| SCHEMBL3505352 | 0.73 | LMNA (0.42) | LMNAGRM4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5494908-A | ANTIDEPRESSANT | HOECHST-ROUSSEL PHARMACEUTICAL INCORPORATED (US) | 1996-02-27 | — | — | US | claimed |