Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 14/20 | 0.39 |
| ▸ | HTR7 | P34969 | 13/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 10/20 | 0.39 |
| ▸ | DRD2 | P14416 | 7/20 | 0.39 |
| ▸ | CASR | P41180 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3504376 | 0.80 | GRM4 (0.41) | HTR2AHTR7KCNH2ALDH1A1 | |
| SCHEMBL3508765 | 0.79 | ALDH1A1 (0.43) | ALDH1A1 | |
| SCHEMBL9085384 | 0.78 | POLB (0.47) | CASRALDH1A1 | |
| SCHEMBL6951008 | 0.78 | HRH3 (0.41) | HTR2AHTR7KCNH2DRD2ALDH1A1 | |
| SCHEMBL6956977 | 0.77 | ACHE (0.39) | HTR2ADRD2CASRALDH1A1 | |
| SCHEMBL3505500 | 0.77 | ALDH1A1 (0.43) | ALDH1A1 | |
| SCHEMBL3505067 | 0.76 | ACHE (0.40) | HTR2AKCNH2DRD2ALDH1A1 | |
| SCHEMBL3505169 | 0.76 | CASR (0.42) | HTR2AHTR7KCNH2CASRALDH1A1 | |
| SCHEMBL3505352 | 0.76 | LMNA (0.42) | HTR2AHTR7DRD2ALDH1A1 | |
| SCHEMBL8947062 | 0.75 | ACHE (0.42) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100247543-A1 | TREATMENT AND PREVENTION OF NEURODEGENERATIVE DISEASES | ORYZON GENOMICS, S.A. (ES) | 2010-09-30 | — | — | US | disclosed |