Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 7/20 | 0.46 |
| ▸ | HSD11B2 | P80365 | 3/20 | 0.44 |
| ▸ | MCHR2 | Q969V1 | 8/20 | 0.44 |
| ▸ | DRD2 | P14416 | 2/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.37 |
| ▸ | UBA1 | P22314 | 1/20 | 0.35 |
| ▸ | NAE1 | Q13564 | 1/20 | 0.35 |
| ▸ | UBA3 | Q8TBC4 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8314152 | 0.85 | NAE1 (0.47) | HSD11B1MCHR2NAE1UBA3 | |
| SCHEMBL8100165 | 0.81 | MCHR2 (0.42) | HSD11B1HSD11B2MCHR2DRD2SLC6A4 | |
| SCHEMBL3545455 | 0.79 | MCHR2 (0.56) | HSD11B1HSD11B2MCHR2DRD2SLC6A4 | |
| SCHEMBL1223056 | 0.78 | HSD11B1 (0.56) | HSD11B1HSD11B2MCHR2KCNH2 | |
| SCHEMBL9395018 | 0.76 | HSD11B1 (0.64) | HSD11B1HSD11B2KCNH2 | |
| SCHEMBL5314192 | 0.75 | HSD11B1 (0.47) | HSD11B1HSD11B2MCHR2KCNH2 | |
| SCHEMBL5314195 | 0.75 | HSD11B1 (0.47) | HSD11B1HSD11B2MCHR2KCNH2 | |
| SCHEMBL1223765 | 0.73 | HSD11B1 (0.56) | HSD11B1HSD11B2KCNH2 | |
| SCHEMBL2758250 | 0.73 | MCHR2 (0.60) | HSD11B1HSD11B2MCHR2DRD2SLC6A4 | |
| SCHEMBL12385458 | 0.73 | MCHR2 (0.50) | MCHR2DRD2SLC6A4KCNH2NAE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5578593-A | RELEASING GROWTH HORMONES FOR ANIMALS | MERCK & CO., INC. (US) | 1996-11-26 | — | — | US | disclosed |