Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VKORC1 | Q9BQB6 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 4/20 | 0.37 |
| ▸ | MGAM | O43451 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | SI | P14410 | 1/20 | 0.35 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | GABRP | O00591 | 1/20 | 0.33 |
| ▸ | GABRD | O14764 | 1/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.33 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.33 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9089870 | 0.84 | MAOA (0.39) | MAOAMGAMGAASIMGAM2 | |
| SCHEMBL10433595 | 0.70 | EYA3 (0.45) | MAOAMGAMGAASIMGAM2 | |
| SCHEMBL3409621 | 0.68 | MAOB (0.50) | GAAALDH1A1KDM4EMEN1LMNA | |
| SCHEMBL29577269 | 0.67 | TSHR (0.44) | ALDH1A1PKMPOLBKDM4ELMNA | |
| SCHEMBL4202389 | 0.67 | TSHR (0.44) | ALDH1A1PKMPOLBKDM4ELMNA | |
| SCHEMBL28168547 | 0.67 | TSHR (0.36) | ALDH1A1PKMPOLBKDM4EMEN1 | |
| SCHEMBL92352 | 0.66 | IDO1 (0.39) | GAAALDH1A1PKMPOLBKDM4E | |
| SCHEMBL2963907 | 0.66 | ALDH1A1 (0.45) | MAOAALDH1A1GABRPGABRDGABRA1 | |
| SCHEMBL8988143 | 0.66 | IAPP (0.50) | CA12CA9GABRA1GABRB2 | |
| SCHEMBL18904514 | 0.66 | MAPT (0.40) | VKORC1GAAALDH1A1PKMPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5559231-A | PHOTOCHROMIC, RECORDING MATERIAL, CLOTHING, GLASSES, WINDOWS | TORAY INDUSTRIES, INC. (JP) | 1996-09-24 | — | — | US | disclosed |
| EP-0358774-B1 | NOVEL SPIROOXAZINE COMPOUNDS | TORAY INDUSTRIES (JP) | 1995-10-25 | — | — | EP | disclosed |
| US-5374723-A | Photochromic dyes; resistance to repetition of coloration and discoloration | TORAY INDUSTRIES, INC. (JP) | 1994-12-20 | — | — | US | disclosed |
| EP-0358774-A1 | NOVEL SPIROOXAZINE COMPOUNDS | TORAY INDUSTRIES, INC. (JP) | 1990-03-21 | — | — | EP | disclosed |