Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.39 |
| ▸ | PDE4A | P27815 | 1/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1999919 | 0.83 | POLB (0.53) | KMT2AMEN1TSHRLMNASMN1; SMN2 | |
| SCHEMBL29889833 | 0.83 | POLB (0.53) | KMT2AMEN1TSHRLMNASMN1; SMN2 | |
| SCHEMBL28222557 | 0.82 | L3MBTL1 (0.54) | KMT2AMEN1HPGDL3MBTL1ALDH1A1 | |
| SCHEMBL18304343 | 0.79 | PTGS2 (0.47) | KMT2AMEN1RAB9ASMN1; SMN2L3MBTL1 | |
| SCHEMBL28209569 | 0.77 | MRGPRX4 (0.49) | LMNAL3MBTL1ALDH1A1 | |
| SCHEMBL1822253 | 0.77 | ALDH1A1 (0.39) | KMT2AMEN1LMNAL3MBTL1ALDH1A1 | |
| SCHEMBL1876225 | 0.77 | L3MBTL1 (0.41) | KMT2ALMNASMN1; SMN2L3MBTL1ALDH1A1 | |
| SCHEMBL11392218 | 0.76 | ALDH1A1 (0.37) | KMT2AMEN1LMNAHPGDSMN1; SMN2 | |
| SCHEMBL9537251 | 0.76 | KMT2A (0.42) | KMT2AMEN1RAB9ATSHRHPGD | |
| SCHEMBL28831706 | 0.76 | L3MBTL1 (0.43) | KMT2AMEN1RAB9ALMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7935815-B2 | Imidazoyl pyridine compounds and salts thereof | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2011-05-03 | — | — | US | disclosed |
| US-20110009619-A1 | POLYCYCLIC COMPOUND | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2011-01-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110009619-A1 | POLYCYCLIC COMPOUND | APP, BACE1, PSEN1 | KMT2A 1666/4885MEN1 424/4885RAB9A 2861/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.