Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | ESRRB | O95718 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | AKT1 | P31749 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Indoline SCHEMBL8918364 | 0.88 | ALDH1A1 (0.49) | NOTUMALDH1A1CYP1A2KDM4EMAPK1 | |
| Succinic Acid Monobenzyl Ester SCHEMBL8919869 | 0.83 | NOTUM (0.50) | NOTUMALDH1A1CYP1A2LMNAMAPK1 | |
| Indoline SCHEMBL28301724 | 0.82 | ALDH1A1 (0.45) | NOTUMALDH1A1CYP1A2KDM4EMAPK1 | |
| Indoline SCHEMBL8922922 | 0.81 | MAPK1 (0.40) | ALDH1A1CYP1A2MAPK1KMT2AMEN1 | |
| Indoline SCHEMBL27915873 | 0.81 | MEN1 (0.44) | MAPK1KMT2AMEN1SMN1; SMN2 | |
| Indoline SCHEMBL28278331 | 0.81 | MEN1 (0.44) | MAPK1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL9755818 | 0.80 | NOTUM (0.51) | NOTUMALDH1A1CYP1A2ESRRBLMNA | |
| Indoline SCHEMBL17652456 | 0.78 | DRD2 (0.44) | NOTUMALDH1A1CYP1A2KDM4EMAPK1 | |
| Indoline SCHEMBL5069264 | 0.75 | PARP10 (0.44) | ALDH1A1CYP1A2LMNAKDM4EMAPK1 | |
| Indoline SCHEMBL28004429 | 0.75 | BRD4 (0.40) | ALDH1A1CYP1A2MAPK1HSD17B10SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5559247-A | Carboxylate and heat-sensitive recording material using same | MITSUI TOATSU CHEMICALS, INC. (JP) | 1996-09-24 | — | — | US | disclosed |