Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 1/20 | 0.40 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | HK1 | P19367 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | GALK1 | P51570 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.33 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.33 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28552531 | 0.67 | AHR (0.50) | AHRPDK2NPC1MEN1KMT2A | |
| SCHEMBL10969348 | 0.64 | HTR5A (0.41) | AHRPDK2NPC1MEN1KMT2A | |
| SCHEMBL28517190 | 0.63 | PDGFRA (0.35) | AHRPDK2NPC1MEN1KMT2A | |
| SCHEMBL6136738 | 0.61 | AHR (0.48) | AHRPDK2NPC1MEN1KMT2A | |
| SCHEMBL4579346 | 0.61 | AHR (0.59) | AHRPDK2NPC1MEN1KMT2A | |
| SCHEMBL8479181 | 0.60 | AHR (0.41) | AHRPDK2NPC1MEN1KMT2A | |
| SCHEMBL1816980 | 0.60 | AHR (0.63) | AHRPDK2NPC1MEN1KMT2A | |
| SCHEMBL8481873 | 0.60 | AHR (0.41) | AHRPDK2NPC1MEN1KMT2A | |
| Oxindole SCHEMBL19504 | 0.59 | AHR (1.00) | AHRPDK2NPC1MEN1KMT2A | |
| Oxindole SCHEMBL1144643 | 0.59 | AHR (1.00) | AHRPDK2NPC1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996010015-A1 | CRYPTOLEPINE ANALOGS WITH HYPOGLYCEMIC ACTIVITY | SHAMAN PHARMACEUTICALS, INC. (US) | 1996-04-04 | — | — | WO | disclosed |