Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR5A | P47898 | 4/20 | 0.41 |
| ▸ | AHR | P35869 | 1/20 | 0.39 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 2/20 | 0.38 |
| ▸ | CREBBP | Q92793 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.38 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.38 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28517190 | 0.82 | PDGFRA (0.35) | AHRPDK2BRD4CREBBPNPC1 | |
| SCHEMBL28552531 | 0.73 | AHR (0.50) | HTR5AAHRPDK2BRD4CREBBP | |
| SCHEMBL6775003 | 0.72 | CA12 (0.49) | CA12CA9KDM4E | |
| SCHEMBL8872856 | 0.71 | CA12 (0.55) | HTR5AAHRPDK2BRD4CREBBP | |
| SCHEMBL7982185 | 0.70 | MEN1 (0.48) | AHRPDK2BRD4CREBBPNPC1 | |
| SCHEMBL45104 | 0.69 | HTR5A (0.53) | HTR5AAHRPDK2BRD4CREBBP | |
| SCHEMBL6136738 | 0.66 | AHR (0.48) | HTR5AAHRPDK2BRD4CREBBP | |
| SCHEMBL9211112 | 0.65 | ALOX5 (0.44) | BRD4CREBBPMAPTGAANPSR1 | |
| SCHEMBL310398 | 0.65 | HTR5A (0.57) | HTR5AAHRPDK2BRD4CREBBP | |
| SCHEMBL9094422 | 0.64 | AHR (0.40) | AHRPDK2BRD4CREBBPNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4556653-A | ANTISECRETORY, ANTIULCER AND ANTISPASMODIC AGENTS | DOMPE' FARMACEUTICA S.P.A. (IT) | 1985-12-03 | — | — | US | disclosed |