Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.60 |
| ▸ | MAPT | P10636 | 4/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.60 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | DRD2 | P14416 | 1/20 | 0.54 |
| ▸ | DRD4 | P21917 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | ACHE | P22303 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9096336 | 0.99 | ALDH1A1 (0.58) | ALDH1A1MAPTKMT2AL3MBTL1ALDH3A1 | |
| SCHEMBL9095464 | 0.98 | ALDH1A1 (0.60) | ALDH1A1MAPTKMT2AL3MBTL1ALDH3A1 | |
| SCHEMBL9096191 | 0.93 | DRD2 (0.62) | ALDH1A1MAPTKMT2AL3MBTL1ALDH3A1 | |
| Hydrochloric Acid SCHEMBL9096767 | 0.92 | DRD2 (0.61) | ALDH1A1MAPTKMT2AL3MBTL1ALDH3A1 | |
| SCHEMBL11147296 | 0.84 | DRD2 (0.63) | ALDH1A1MAPTKMT2AL3MBTL1LMNA | |
| SCHEMBL9096391 | 0.84 | ACHE (0.63) | ALDH1A1MAPTKMT2AL3MBTL1LMNA | |
| SCHEMBL27378723 | 0.82 | ALDH3A1 (0.56) | ALDH1A1ALDH3A1DRD2DRD4 | |
| Hydrochloric Acid SCHEMBL9095750 | 0.82 | ALDH3A1 (0.72) | ALDH1A1ALDH3A1DRD2DRD4 | |
| SCHEMBL9098897 | 0.82 | ALDH3A1 (0.57) | ALDH1A1MAPTKMT2AALDH3A1LMNA | |
| SCHEMBL15215065 | 0.82 | ALDH1A1 (0.70) | ALDH1A1MAPTKMT2AL3MBTL1ALDH3A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5585378-A | Composition containing an oxoindole compound | AKTIEBOLAGET ASTRA (SE) | 1996-12-17 | — | — | US | disclosed |