Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL909656 | 0.91 | TSHR (0.36) | TSHRFFAR4PTGS2ALDH1A1LMNA | |
| SCHEMBL910148 | 0.84 | TSHR (0.36) | TSHRFFAR4PTGS2ALDH1A1LMNA | |
| SCHEMBL9534360 | 0.82 | TSHR (0.36) | TSHRFFAR4PTGS2ALDH1A1LMNA | |
| SCHEMBL9535324 | 0.78 | TSHR (0.42) | TSHR | |
| SCHEMBL7850191 | 0.78 | FFAR4 (0.40) | TSHRFFAR4PTGS2ALDH1A1 | |
| SCHEMBL8901312 | 0.77 | PTGS2 (0.34) | TSHRFFAR4PTGS2ALDH1A1LMNA | |
| Metosulam SCHEMBL23302655 | 0.76 | TSHR (0.41) | TSHRFFAR4ALDH1A1LMNA | |
| Metosulam SCHEMBL29516826 | 0.76 | TSHR (0.41) | TSHRFFAR4ALDH1A1LMNA | |
| Metosulam SCHEMBL55076 | 0.76 | TSHR (0.41) | TSHRFFAR4ALDH1A1LMNA | |
| SCHEMBL9536906 | 0.76 | SMN1; SMN2 (0.34) | TSHRPTGS2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999000020-A1 | 3-(5-TETRAZOLYL CARBONYL)-2-QUINOLONES AND PRODUCTS FOR PROTECTING USEFUL PLANTS CONTAINING THE SAME | HOECHST SCHERING AGREVO GMBH (DE) | 1999-01-07 | — | — | WO | disclosed |