Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 3/20 | 0.33 |
| ▸ | PDE3A | Q14432 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9096832 | 0.79 | PDE3B (0.38) | PDE3BPDE3AHPGD | |
| SCHEMBL9095629 | 0.79 | PDE3B (0.34) | PDE3BPDE3AHPGD | |
| SCHEMBL9096470 | 0.74 | HPGD (0.50) | PDE3BPDE3AHPGD | |
| SCHEMBL9094190 | 0.72 | BRD4 (0.33) | CA2 | |
| SCHEMBL9093732 | 0.70 | ADRB2 (0.35) | HPGD | |
| SCHEMBL15898953 | 0.68 | CA2 (0.36) | CA2 | |
| SCHEMBL12903285 | 0.67 | SMN1; SMN2 (0.38) | LMNACA2 | |
| SCHEMBL9626856 | 0.67 | HPGD (0.50) | PDE3BPDE3ALMNAHPGD | |
| SCHEMBL5102226 | 0.66 | CA2 (0.55) | LMNACA2 | |
| SCHEMBL9626996 | 0.65 | KDM4E (0.50) | PDE3BPDE3AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5576324-A | Quinoline derivatives or salt thereof and remedy for cardiac diseases containing the same | KOWA CO., LTD. (JP) | 1996-11-19 | — | — | US | disclosed |
| EP-0638571-A1 | QUINOLINE DERIVATIVE OR SALT THEREOF AND REMEDY FOR CARDIAC DISEASES CONTAINING THE SAME | KOWA CO. LTD. (JP) | 1995-02-15 | — | — | EP | disclosed |