Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | MGAM | O43451 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | SI | P14410 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.37 |
| ▸ | PDE3B | Q13370 | 6/20 | 0.34 |
| ▸ | PDE3A | Q14432 | 6/20 | 0.34 |
| ▸ | CTSV | O60911 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.31 |
| ▸ | PGR | P06401 | 1/20 | 0.31 |
| ▸ | AR | P10275 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9628439 | 0.80 | L3MBTL1 (0.49) | KDM4ECYP3A4HPGDHSD17B10ALDH1A1 | |
| SCHEMBL9626684 | 0.75 | PDE4D (0.41) | HPGDMAPTPDE3BPDE3AOPRM1 | |
| SCHEMBL9626626 | 0.75 | PDE3B (0.33) | KDM4EHSD17B10PDE3BPDE3A | |
| SCHEMBL9096470 | 0.74 | HPGD (0.50) | KDM4EHPGDALDH1A1MAPTPDE3B | |
| SCHEMBL15444379 | 0.74 | KDM4E (0.65) | KDM4ECYP3A4HPGDHSD17B10ALDH1A1 | |
| SCHEMBL9096832 | 0.71 | PDE3B (0.38) | KDM4EHPGDALDH1A1PDE3BPDE3A | |
| SCHEMBL9626653 | 0.69 | — | — | |
| SCHEMBL9095629 | 0.69 | PDE3B (0.34) | HPGDALDH1A1MAPTPDE3BPDE3A | |
| SCHEMBL9245586 | 0.67 | HTR1A (0.33) | KDM4EHPGDHSD17B10ALDH1A1MAPT | |
| Lomatin SCHEMBL6273711 | 0.67 | KDM4E (1.00) | KDM4ECYP3A4HPGDHSD17B10ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5093339-A | Anticoagulant, hypotensive, antiangina, antiasthma, antiulcer, anti-platelet activating factor | KODAMA KABUSHIKI KAISHA (JP) | 1992-03-03 | — | — | US | disclosed |