Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | ALPG | P10696 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | PDE3B | Q13370 | 6/20 | 0.36 |
| ▸ | PDE3A | Q14432 | 6/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | AR | P10275 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | NQO2 | P16083 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9096470 | 0.85 | HPGD (0.50) | HPGDALDH1A1MAPTSMN1; SMN2PDE3B | |
| SCHEMBL9628449 | 0.72 | HTR2A (0.41) | HPGDALDH1A1MAPTCA1CA9 | |
| SCHEMBL9626684 | 0.71 | PDE4D (0.41) | HPGDMAPTPDE3BPDE3ALMNA | |
| SCHEMBL9096832 | 0.70 | PDE3B (0.38) | HPGDALDH1A1CYP1A2CYP2D6ALPG | |
| SCHEMBL9095629 | 0.70 | PDE3B (0.34) | HPGDALDH1A1MAPTCYP1A2CYP2D6 | |
| SCHEMBL9097597 | 0.67 | PDE3B (0.33) | HPGDPDE3BPDE3ALMNA | |
| SCHEMBL9626996 | 0.67 | KDM4E (0.50) | HPGDALDH1A1MAPTPDE3BPDE3A | |
| SCHEMBL9626626 | 0.66 | PDE3B (0.33) | CA1CA9PDE3BPDE3AKDM4E | |
| SCHEMBL9627284 | 0.64 | MAP3K14 (0.42) | ALDH1A1CA1CA9PDE3BPDE3A | |
| SCHEMBL13443211 | 0.63 | HPGD (0.40) | HPGDALDH1A1MAPTCA1CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5093339-A | Anticoagulant, hypotensive, antiangina, antiasthma, antiulcer, anti-platelet activating factor | KODAMA KABUSHIKI KAISHA (JP) | 1992-03-03 | — | — | US | disclosed |
| EP-0355689-A2 | Pyrano [f] quinoline derivatives and pharmaceutical compositions containing the same | KODAMA KABUSHIKI KAISHA (JP) | 1990-02-28 | — | — | EP | disclosed |