Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | BRD4 | O60885 | 3/20 | 0.38 |
| ▸ | CREBBP | Q92793 | 3/20 | 0.38 |
| ▸ | PDE3B | Q13370 | 5/20 | 0.37 |
| ▸ | PDE3A | Q14432 | 5/20 | 0.37 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | AR | P10275 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 3/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9626856 | 0.85 | HPGD (0.50) | HPGDALDH1A1MAPTKDM4EPDE3B | |
| SCHEMBL9095629 | 0.78 | PDE3B (0.34) | HPGDALDH1A1MAPTPDE3BPDE3A | |
| SCHEMBL9626626 | 0.77 | PDE3B (0.33) | KDM4EPDE3BPDE3A | |
| SCHEMBL9626996 | 0.74 | KDM4E (0.50) | HPGDALDH1A1MAPTKDM4EPDE3B | |
| SCHEMBL9097597 | 0.74 | PDE3B (0.33) | HPGDPDE3BPDE3A | |
| SCHEMBL9245586 | 0.71 | HTR1A (0.33) | HPGDALDH1A1MAPTKDM4EPDE3B | |
| SCHEMBL9628449 | 0.71 | HTR2A (0.41) | HPGDALDH1A1MAPTKDM4EPDE3B | |
| SCHEMBL9626684 | 0.68 | PDE4D (0.41) | HPGDMAPTPDE3BPDE3A | |
| SCHEMBL12203811 | 0.66 | NISCH (0.50) | HPGDALDH1A1MAPTKDM4EMEN1 | |
| SCHEMBL8122273 | 0.65 | ALDH1A1 (0.44) | HPGDALDH1A1MAPTKDM4EBRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5576324-A | Quinoline derivatives or salt thereof and remedy for cardiac diseases containing the same | KOWA CO., LTD. (JP) | 1996-11-19 | — | — | US | disclosed |
| EP-0638571-A1 | QUINOLINE DERIVATIVE OR SALT THEREOF AND REMEDY FOR CARDIAC DISEASES CONTAINING THE SAME | KOWA CO. LTD. (JP) | 1995-02-15 | — | — | EP | disclosed |