Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH3A1 | P30838 | 5/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.69 |
| ▸ | DRD2 | P14416 | 2/20 | 0.67 |
| ▸ | DRD4 | P21917 | 2/20 | 0.67 |
| ▸ | TP53 | P04637 | 1/20 | 0.62 |
| ▸ | ALDH2 | P05091 | 2/20 | 0.60 |
| ▸ | PKM | P14618 | 1/20 | 0.60 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.58 |
| ▸ | CES1 | P23141 | 1/20 | 0.58 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.57 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.57 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.57 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.57 |
| ▸ | DRD3 | P35462 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9095750 | 0.95 | ALDH3A1 (0.72) | ALDH3A1ALDH1A1DRD2DRD4ALDH2 | |
| SCHEMBL9095875 | 0.89 | DRD2 (0.83) | ALDH3A1ALDH1A1DRD2DRD4TP53 | |
| SCHEMBL9235424 | 0.88 | DRD2 (0.86) | ALDH3A1ALDH1A1DRD2DRD4CES1 | |
| Hydrochloric Acid SCHEMBL11144969 | 0.87 | DRD2 (0.84) | ALDH3A1ALDH1A1DRD2DRD4CES1 | |
| SCHEMBL9095464 | 0.82 | ALDH1A1 (0.60) | ALDH3A1ALDH1A1DRD2DRD4 | |
| SCHEMBL9096430 | 0.82 | ALDH3A1 (1.00) | ALDH3A1ALDH1A1DRD2DRD4ALDH2 | |
| SCHEMBL7986385 | 0.82 | ADRA1D (0.70) | — | |
| SCHEMBL27378723 | 0.81 | ALDH3A1 (0.56) | ALDH3A1ALDH1A1DRD2DRD4ALDH2 | |
| Hydrochloric Acid SCHEMBL27531896 | 0.80 | ALDH3A1 (0.55) | ALDH3A1ALDH1A1DRD2DRD4ALDH2 | |
| SCHEMBL9094820 | 0.80 | ALDH1A1 (0.60) | ALDH3A1ALDH1A1DRD2DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5585378-A | Composition containing an oxoindole compound | AKTIEBOLAGET ASTRA (SE) | 1996-12-17 | — | — | US | disclosed |