Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.39 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.38 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.38 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.36 |
| ▸ | PTGIR | P43119 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1387794 | 0.87 | MEN1 (0.42) | KDM4EALDH1A1MEN1KMT2AKEAP1 | |
| SCHEMBL9097562 | 0.82 | S1PR1 (0.50) | ALDH1A1MEN1KMT2ASIGMAR1 | |
| SCHEMBL4558670 | 0.76 | ALDH1A1 (0.50) | KDM4EALDH1A1MEN1KMT2ASIGMAR1 | |
| SCHEMBL7282542 | 0.74 | SIGMAR1 (0.58) | NPC1ALDH1A1RAB9AMEN1KMT2A | |
| SCHEMBL20187534 | 0.74 | CACNA2D1 (0.49) | KDM4EALDH1A1SIGMAR1OPRM1 | |
| SCHEMBL9079737 | 0.73 | HPGD (0.40) | KDM4ENPC1ALDH1A1RAB9AMEN1 | |
| SCHEMBL9079952 | 0.73 | MLYCD (0.40) | KDM4EALDH1A1MEN1KMT2ASIGMAR1 | |
| SCHEMBL6893683 | 0.72 | ALDH1A1 (0.51) | KDM4ENPC1ALDH1A1RAB9AMEN1 | |
| SCHEMBL1387733 | 0.72 | ALDH1A1 (0.43) | KDM4ENPC1ALDH1A1RAB9AMEN1 | |
| SCHEMBL11739827 | 0.71 | NPC1 (0.49) | NPC1ALDH1A1RAB9AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0702677-A1 | AROMATIC AMIDE COMPOUNDS AND METAL CHELATES THEREOF | BRACCO International B.V. (NL) | 1996-03-27 | — | — | EP | claimed |