Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MLYCD | O95822 | 2/20 | 0.40 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | PTGES | O14684 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | DRD4 | P21917 | 1/20 | 0.36 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.36 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1387848 | 0.87 | RXRA (0.38) | KMT2AMEN1ALDH1A1KDM4ETSHR | |
| SCHEMBL1387794 | 0.85 | MEN1 (0.42) | KMT2AMEN1ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL20187534 | 0.83 | CACNA2D1 (0.49) | ALDH1A1LMNAKDM4ETSHRDRD4 | |
| SCHEMBL1387733 | 0.81 | ALDH1A1 (0.43) | MLYCDKMT2AMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL9080067 | 0.79 | ALDH1A1 (0.42) | MLYCDKMT2AMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL1387663 | 0.77 | S1PR1 (0.63) | KMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL1387857 | 0.76 | ALDH1A1 (0.43) | ALDH1A1SMN1; SMN2LMNAOPRM1 | |
| SCHEMBL22403100 | 0.75 | CACNA2D1 (0.45) | KMT2AMEN1ALDH1A1KDM4ETSHR | |
| SCHEMBL13757716 | 0.75 | MLYCD (0.48) | MLYCDNR1H4KMT2AMEN1ALDH1A1 | |
| SCHEMBL9079285 | 0.75 | S1PR1 (0.61) | KMT2AMEN1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5573752-A | Aromatic amide compounds and metal chelates thereof | BRACCO INTERNATIONAL B.V. | 1996-11-12 | — | — | US | disclosed |
| EP-0702677-A1 | AROMATIC AMIDE COMPOUNDS AND METAL CHELATES THEREOF | BRACCO International B.V. (NL) | 1996-03-27 | — | — | EP | disclosed |
| WO-1995027705-A1 | AROMATIC AMIDE COMPOUNDS AND METAL CHELATES THEREOF | BRACCO INTERNATIONAL B.V. (NL) | 1995-10-19 | — | — | WO | disclosed |