Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | HPGD | P15428 | 4/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | AHR | P35869 | 2/20 | 0.39 |
| ▸ | BCAT1 | P54687 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | TTR | P02766 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9101496 | 0.83 | MEN1 (0.39) | MAPTKDM4EHPGDNPC1MEN1 | |
| SCHEMBL9101266 | 0.80 | MAPT (0.41) | MAPTKDM4EHPGDNPC1MEN1 | |
| SCHEMBL362964 | 0.75 | TSHR (0.43) | KDM4EMEN1KMT2AALDH1A1CYP1A2 | |
| SCHEMBL31558552 | 0.74 | NPC1 (0.50) | MAPTKDM4EHPGDNPC1MEN1 | |
| SCHEMBL12060916 | 0.71 | MAPT (0.53) | MAPTKDM4EHPGDNPC1MEN1 | |
| SCHEMBL11574355 | 0.70 | CYP19A1 (0.49) | KDM4ENPC1RAB9ALMNAHSD17B10 | |
| SCHEMBL7734271 | 0.70 | CYP2C9 (0.48) | NPC1ALDH1A1RAB9ATSHR | |
| SCHEMBL26629595 | 0.70 | ESR1 (0.52) | HPGDNPC1MEN1KMT2AALDH1A1 | |
| SCHEMBL9251887 | 0.70 | CYP19A1 (0.43) | MAPTKDM4EHPGDNPC1MEN1 | |
| SCHEMBL7816281 | 0.69 | KIF11 (0.44) | MAPTHPGDNPC1SMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5552091-A | PHOTOCHROMIC, LENSES | PPG INDUSTRIES, INC. (US) | 1996-09-03 | — | — | US | disclosed |