Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 3/20 | 0.43 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | FLT3 | P36888 | 1/20 | 0.38 |
| ▸ | MGLL | Q99685 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | MAOB | P27338 | 3/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | CA12 | O43570 | 2/20 | 0.37 |
| ▸ | CA9 | Q16790 | 2/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA3 | P07451 | 1/20 | 0.37 |
| ▸ | CA4 | P22748 | 1/20 | 0.37 |
| ▸ | CA6 | P23280 | 1/20 | 0.37 |
| ▸ | CA5A | P35218 | 1/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9258611 | 0.81 | CYP19A1 (0.41) | CYP19A1CYP2A6KDM4EFLT3MGLL | |
| SCHEMBL9258680 | 0.77 | RAB9A (0.41) | CYP19A1KDM4EHSD17B10TDP1RAB9A | |
| SCHEMBL362964 | 0.73 | TSHR (0.43) | KDM4ETSHRMEN1KMT2AALDH1A1 | |
| SCHEMBL13713849 | 0.71 | CYP19A1 (0.42) | CYP19A1CYP2A6KDM4EFLT3MGLL | |
| SCHEMBL8036000 | 0.71 | KDM4E (0.46) | CYP19A1CYP2A6KDM4EFLT3MGLL | |
| SCHEMBL10472895 | 0.70 | FLT3 (0.50) | CYP2A6KDM4EFLT3MGLLHSD17B10 | |
| SCHEMBL28750544 | 0.70 | MAPT (0.45) | CYP19A1CYP2A6KDM4EFLT3MGLL | |
| SCHEMBL9100003 | 0.70 | MAPT (0.42) | KDM4EHSD17B10TDP1RAB9ATSHR | |
| SCHEMBL28018770 | 0.69 | KDM4E (0.44) | CYP19A1CYP2A6KDM4EFLT3MGLL | |
| SCHEMBL8696581 | 0.69 | CYP19A1 (0.65) | CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5459149-A | Penta-2,4-dienamides and use as pesticides | ROUSSEL UCLAF (FR) | 1995-10-17 | — | — | US | disclosed |
| US-5429774-A | FOR USE IN PHOTOCHROMIC ARTICLES | TRANSITIONS OPTICAL, INC. (US) | 1995-07-04 | — | — | US | disclosed |