Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.39 |
| ▸ | NPC1 | O15118 | 4/20 | 0.39 |
| ▸ | HPGD | P15428 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | AHR | P35869 | 2/20 | 0.36 |
| ▸ | CDC14B | O60729 | 2/20 | 0.35 |
| ▸ | CDC14A | Q9UNH5 | 2/20 | 0.35 |
| ▸ | IDO1 | P14902 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | BCAT1 | P54687 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9100003 | 0.83 | MAPT (0.42) | MEN1KMT2ANPC1HPGDMAPT | |
| SCHEMBL9101266 | 0.81 | MAPT (0.41) | MEN1KMT2ANPC1HPGDMAPT | |
| SCHEMBL9670139 | 0.73 | KCNN4 (0.47) | KDM4EALDH1A1 | |
| SCHEMBL8718999 | 0.73 | KMT2A (0.39) | MEN1KMT2ASMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL9258611 | 0.71 | CYP19A1 (0.41) | MEN1KMT2ANPC1HPGDMAPT | |
| SCHEMBL7122472 | 0.71 | NFE2L2 (0.38) | MEN1KMT2ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL31558552 | 0.70 | NPC1 (0.50) | MEN1KMT2ANPC1HPGDMAPT | |
| SCHEMBL7807844 | 0.70 | PRKCI (0.38) | NPC1MAPTRAB9AKDM4E | |
| SCHEMBL7816756 | 0.69 | CYP19A1 (0.40) | MEN1KMT2AMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL7123446 | 0.68 | RELA (0.42) | MEN1KMT2ANPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5552091-A | PHOTOCHROMIC, LENSES | PPG INDUSTRIES, INC. (US) | 1996-09-03 | — | — | US | disclosed |