Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 6/20 | 0.36 |
| ▸ | RAB9A | P51151 | 5/20 | 0.36 |
| ▸ | MAOB | P27338 | 2/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.35 |
| ▸ | FLT3 | P36888 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MGLL | Q99685 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | MGAM | O43451 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | SI | P14410 | 1/20 | 0.34 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | TYR | P14679 | 1/20 | 0.34 |
| ▸ | DAO | P14920 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9251887 | 0.81 | CYP19A1 (0.43) | CYP19A1NPC1RAB9AMAOBCYP2A6 | |
| SCHEMBL9258680 | 0.80 | RAB9A (0.41) | CYP19A1NPC1RAB9AMAOBMAOA | |
| SCHEMBL9101496 | 0.71 | MEN1 (0.39) | NPC1RAB9AMAOAKDM4EGAA | |
| SCHEMBL9670139 | 0.70 | KCNN4 (0.47) | KDM4ETSHRALDH1A1 | |
| SCHEMBL8036000 | 0.68 | KDM4E (0.46) | CYP19A1NPC1RAB9AMAOBMAOA | |
| SCHEMBL28750544 | 0.67 | MAPT (0.45) | CYP19A1NPC1RAB9AMAOBMAOA | |
| SCHEMBL676612 | 0.67 | KDM4E (0.45) | CYP19A1NPC1RAB9AMAOBMAOA | |
| SCHEMBL28018770 | 0.66 | KDM4E (0.44) | CYP19A1NPC1RAB9AMAOBMAOA | |
| SCHEMBL7122472 | 0.65 | NFE2L2 (0.38) | NPC1RAB9ATSHRSMN1; SMN2ALDH1A1 | |
| SCHEMBL8703062 | 0.64 | CYP19A1 (0.58) | CYP19A1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5429774-A | FOR USE IN PHOTOCHROMIC ARTICLES | TRANSITIONS OPTICAL, INC. (US) | 1995-07-04 | — | — | US | disclosed |