Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G7 | Q13093 | 10/20 | 0.34 |
| ▸ | PTGDR | Q13258 | 4/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.31 |
| ▸ | CNR2 | P34972 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9103212 | 0.85 | CYP3A4 (0.42) | PLA2G7PTGDRCYP3A4 | |
| SCHEMBL9109999 | 0.85 | CNR2 (0.40) | PLA2G7CNR2 | |
| SCHEMBL9889714 | 0.82 | LMNA (0.37) | PLA2G7PTGDRCYP3A4CNR2 | |
| SCHEMBL9889704 | 0.80 | CYP2C9 (0.40) | CYP3A4 | |
| SCHEMBL9889697 | 0.80 | LYN (0.39) | PTGDRCYP3A4CNR2 | |
| SCHEMBL9101618 | 0.80 | PLA2G7 (0.41) | PLA2G7PTGDRCYP3A4CNR2 | |
| SCHEMBL9106828 | 0.80 | PLA2G7 (0.48) | PLA2G7CYP3A4CNR2 | |
| SCHEMBL9107940 | 0.78 | PLAAT3 (0.42) | CYP3A4 | |
| SCHEMBL9108510 | 0.77 | CSF1R (0.37) | PTGDRCNR2 | |
| SCHEMBL9889713 | 0.74 | LMNA (0.35) | PLA2G7PTGDRCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120142717-A1 | COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2012-06-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120142717-A1 | COMPOUNDS | LIPG, PLA2G1B, ENPP2 | PLA2G7 6/4885PTGDR 314/4885CYP3A4 4134/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.