Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3BCHECHRM1CHRM2CHRM3CHRM4CHRNA3CHRNA4CHRNB2CHRNB4ESR1ESR2GABRA1GABRB1GABRG2GBA1GHSRHRH1HTR1DHTR2AMAOBOPRD1OPRK1OPRM1SLC6A2SLC6A3TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8UGCGrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Cadaverine Tartrate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB known ✓ | P27338 | 1/20 | 0.46 |
| ▸ | BCHE known ✓ | P06276 | 1/20 | 0.41 |
| ▸ | ACHE known ✓ | P22303 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 6/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | CES2 | O00748 | 2/20 | 0.42 |
| ▸ | CES1 | P23141 | 2/20 | 0.42 |
| ▸ | IKBKB | O14920 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 7/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.41 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
| ▸ | ALPG | P10696 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29929890 | 0.82 | LMNA (0.56) | MEN1KMT2ARAB9ANPC1MAOA | |
| SCHEMBL57616 | 0.82 | LMNA (0.56) | MEN1KMT2ARAB9ANPC1MAOA | |
| Methyl Alcohol SCHEMBL28005405 | 0.80 | MEN1 (0.52) | MEN1KMT2ARAB9ANPC1MAOA | |
| SCHEMBL5167846 | 0.76 | LMNA (0.54) | MEN1KMT2ARAB9ANPC1MAOA | |
| SCHEMBL2760792 | 0.76 | LMNA (0.54) | MEN1KMT2ARAB9ANPC1MAOA | |
| SCHEMBL31677837 | 0.76 | LMNA (0.54) | MEN1KMT2ARAB9ANPC1MAOA | |
| SCHEMBL28122579 | 0.74 | TSHR (0.59) | MAOBMAPTPOLBTHRBGAA | |
| SCHEMBL28688755 | 0.74 | TSHR (0.47) | MEN1KMT2ARAB9ANPC1MAOA | |
| SCHEMBL3829978 | 0.72 | TSHR (0.56) | MAOBMAPTPOLBTHRBGAA | |
| SCHEMBL31268220 | 0.70 | MAOA (0.60) | MEN1KMT2AMAOAMAOBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5496736-A | COLORIMETRIC | HYBRIVET SYSTEMS, INC. (US) | 1996-03-05 | — | — | US | disclosed |
| US-5445965-A | Detection of nutrients and contaminants in liquid sample | HYBRIVET SYSTEMS, INC. (US) | 1995-08-29 | — | — | US | disclosed |