SCHEMBL9103614

SCHEMBL9103614

Cn1c2ccccc2c2cc(C#N)ccc21

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR3 P46089 1/20 0.57
MEN1 O00255 3/20 0.53
KMT2A Q03164 3/20 0.53
KDM4E B2RXH2 2/20 0.53
MAPT P10636 2/20 0.53
L3MBTL1 Q9Y468 2/20 0.53
ALDH1A1 P00352 1/20 0.53
HPGD P15428 1/20 0.53
HTT P42858 1/20 0.53
HSD17B10 Q99714 1/20 0.53
NPC1 O15118 3/20 0.49
RAB9A P51151 3/20 0.49
EGFR P00533 2/20 0.47
SRC P12931 2/20 0.47
HCRTR1 O43613 2/20 0.47
PTGER4 P35408 2/20 0.46
ENPP3 O14638 1/20 0.45
RORC P51449 1/20 0.44
PABPC1 P11940 1/20 0.44
KIF11 P52732 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6363289 0.91 EGFR (0.46) GPR3MEN1KMT2AKDM4EMAPT
SCHEMBL29858321 0.91 EGFR (0.46) GPR3MEN1KMT2AKDM4EMAPT
SCHEMBL17115408 0.89 GPR3 (0.46) GPR3MEN1KMT2AKDM4EMAPT
SCHEMBL18030982 0.89 GPR3 (0.46) GPR3MEN1KMT2AKDM4EMAPT
SCHEMBL17034459 0.89 GPR3 (0.46) GPR3MEN1KMT2AKDM4EMAPT
SCHEMBL17032695 0.89 GPR3 (0.57) GPR3MEN1KMT2AKDM4EMAPT
SCHEMBL11807938 0.87 EGFR (0.42) GPR3MEN1KMT2AKDM4EMAPT
SCHEMBL18031027 0.87 GPR3 (0.43) GPR3MEN1KMT2AKDM4EMAPT
SCHEMBL17034462 0.87 GPR3 (0.43) GPR3MEN1KMT2AKDM4EMAPT
SCHEMBL18031009 0.87 GPR3 (0.43) GPR3MEN1KMT2AKDM4EMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230129321-A1 LIGHT EMITTING ELEMENT SAMSUNG DISPLAY CO., LTD. (KR) 2023-04-27 US disclosed
US-20230129321-A1 LIGHT EMITTING ELEMENT SAMSUNG DISPLAY CO., LTD. (KR) 2023-04-27 US disclosed
US-20230131934-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-04-27 US disclosed
EP-4137551-A1 ORGANIC ELECTROLUMINESCENT MATERIAL AND DEVICE THEREOF Beijing Summer Sprout Technology Co., Ltd. (CN) 2023-02-22 EP disclosed
EP-3702349-B1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG ELECTRONICS CO LTD (KR) 2023-01-04 EP disclosed
WO-2022268066-A1 PROTEIN DEGRADATION AGENT 苏州开拓药业股份有限公司 2022-12-29 WO disclosed
EP-3878855-A1 CARBENE COMPOUNDS AND ORGANIC ELECTROLUMINESCENT DEVICES University of Southern California (US) 2021-09-15 EP disclosed
US-10968229-B2 Seven-membered ring compounds IDEMITSU KOSAN CO., LTD. (JP) 2021-04-06 US disclosed
US-10689385-B2 Benzimidazolo[1,2-A]benzimidazole carrying aryl- or arylnitril groups for organic light emitting diodes IDEMITSU KOSAN CO., LTD. (JP) 2020-06-23 US disclosed
EP-3061759-B1 NITRILE SUBSTITUTED DIBENZOFURANS IDEMITSU KOSAN CO (JP) 2019-12-25 EP disclosed
EP-3061759-A1 NITRILE SUBSTITUTED DIBENZOFURANS Idemitsu Kosan Co., Ltd (JP) 2016-08-31 EP disclosed
US-20160248026-A1 NITRILE SUBSTITUTED DIBENZOFURANS IDEMITSU KOSAN CO., LTD. (JP) 2016-08-25 US disclosed
WO-2016097983-A1 1-FUNCTIONALIZED DIBENZOFURANS AND DIBENZOTHIOPHENES FOR ORGANIC LIGHT EMITTING DIODES (OLEDS) IDEMITSU KOSAN CO., LTD. (JP) 2016-06-23 WO disclosed
EP-3034506-A1 4-functionalized carbazole derivatives for electronic applications Idemitsu Kosan Co., Ltd (JP) 2016-06-22 EP disclosed
EP-3034507-A1 1-functionalized dibenzofurans and dibenzothiophenes for organic light emitting diodes (OLEDs) Idemitsu Kosan Co., Ltd (JP) 2016-06-22 EP disclosed
WO-2016079667-A1 INDOLE DERIVATIVES FOR ELECTRONIC APPLICATIONS IDEMITSU KOSAN CO., LTD. (JP) 2016-05-26 WO disclosed
US-20160079546-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2016-03-17 US disclosed
US-20150243903-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2015-08-27 US disclosed
US-20120298932-A1 METAL COMPLEX, COMPOSITION COMPRISING SAME AND LIGHT-EMITTING ELEMENT USING SAME TOKYO INSTITUTE OF TECHNOLOGY (JP) 2012-11-29 US disclosed
EP-2460788-A1 METAL COMPLEX, COMPOSITION COMPRISING SAME AND LIGHT-EMITTING ELEMENT USING SAME Sumitomo Chemical Company, Limited (JP) 2012-06-06 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150243903-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD1, OCIAD2, OSBP GPR3 1146/4885MEN1 4226/4885KMT2A 4554/4885
US-20120298932-A1 METAL COMPLEX, COMPOSITION COMPRISING SAME AND LIGHT-EMITTING ELEMENT USING SAME C1S, AP3M1, AP1M1 GPR3 453/4885MEN1 18/4885KMT2A 2527/4885
US-10968229-B2 Seven-membered ring compounds MCM7, XPO7, LUC7L2 GPR3 3709/4885MEN1 441/4885KMT2A 3830/4885
US-20160079546-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME CRY1, CRY2, CCNE2 GPR3 2989/4885MEN1 465/4885KMT2A 1899/4885
US-20230131934-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD1, OCIAD2, OSBP GPR3 1146/4885MEN1 4226/4885KMT2A 4554/4885
US-10689385-B2 Benzimidazolo[1,2-A]benzimidazole carrying aryl- or arylnitril groups for organic light emitting diodes KCNB1, KCNJ2, KCNB2 GPR3 1117/4885MEN1 3488/4885KMT2A 898/4885
US-20160248026-A1 NITRILE SUBSTITUTED DIBENZOFURANS DBF4, NXF1, NCF1 GPR3 4779/4885MEN1 1469/4885KMT2A 4257/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.