Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.47 |
| ▸ | NPC1 | O15118 | 4/20 | 0.47 |
| ▸ | HTT | P42858 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | PKM | P14618 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | XBP1 | P17861 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.40 |
| ▸ | RELA | Q04206 | 1/20 | 0.40 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.39 |
| ▸ | CCR6 | P51684 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11574942 | 0.72 | RAB9A (0.48) | RAB9ASMN1; SMN2NPC1HTTKMT2A | |
| Oxycarboxin SCHEMBL18897 | 0.70 | RAB9A (0.56) | RAB9ASMN1; SMN2NPC1HTTKMT2A | |
| Oxycarboxin SCHEMBL28267507 | 0.70 | RAB9A (0.56) | RAB9ASMN1; SMN2NPC1HTTKMT2A | |
| SCHEMBL9105045 | 0.69 | MAPK1 (0.52) | RAB9ASMN1; SMN2NPC1HTTKMT2A | |
| SCHEMBL11748829 | 0.68 | RAB9A (0.50) | RAB9ASMN1; SMN2NPC1HTTKMT2A | |
| SCHEMBL9107776 | 0.67 | POLB (0.41) | RAB9ASMN1; SMN2NPC1HTTKMT2A | |
| SCHEMBL11632032 | 0.65 | SMN1; SMN2 (0.66) | RAB9ASMN1; SMN2NPC1HTTKMT2A | |
| SCHEMBL14132673 | 0.64 | KMT2A (1.00) | RAB9ASMN1; SMN2NPC1HTTKMT2A | |
| SCHEMBL11124271 | 0.63 | RAB9A (0.48) | RAB9ASMN1; SMN2NPC1HTTKMT2A | |
| SCHEMBL20512531 | 0.62 | TP53 (0.56) | RAB9ASMN1; SMN2HTTKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120142676-A1 | Oxathiazine and dithiine oxides as inhibitors of sulfhydryl-dependent biomolecules | CHEE GAIK-LEAN (CA) | 2012-06-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120142676-A1 | Oxathiazine and dithiine oxides as inhibitors of sulfhydryl-dependent biomolecules | HPGDS, SHMT1, QSOX1 | RAB9A 4401/4885SMN1; SMN2 4655/4885NPC1 2313/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.