Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.39 |
| ▸ | LTA4H | P09960 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.37 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.37 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.37 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.37 |
| ▸ | PLAAT4 | Q9UL19 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9105245 | 0.97 | ALDH1A1 (0.41) | ALDH1A1KMT2AMAPTKDM4EEPHX2 | |
| SCHEMBL3701709 | 0.92 | HPGD (0.40) | ALDH1A1KMT2AMEN1MAPTPOLB | |
| SCHEMBL9105786 | 0.88 | GPBAR1 (0.33) | ALDH1A1KMT2AMEN1MAPTKDM4E | |
| SCHEMBL3702498 | 0.88 | HPGD (0.39) | ALDH1A1KMT2AMEN1HTTMAPT | |
| SCHEMBL3700736 | 0.86 | BCHE (0.45) | ALDH1A1KMT2AMEN1MAPTKDM4E | |
| SCHEMBL9102458 | 0.86 | MAPT (0.42) | ALDH1A1KMT2AMEN1HTTMAPT | |
| SCHEMBL9104473 | 0.85 | LMNA (0.39) | KMT2AMEN1MAPTKDM4EPOLB | |
| SCHEMBL3702422 | 0.85 | GPBAR1 (0.35) | ALDH1A1 | |
| SCHEMBL3701796 | 0.85 | MEN1 (0.35) | ALDH1A1KMT2AMEN1MAPTKDM4E | |
| SCHEMBL9099926 | 0.84 | HDAC1 (0.32) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2460798-A2 | APAF-1 INHIBITOR COMPOUNDS | Laboratorios SALVAT, S.A. (ES) | 2012-06-06 | — | — | EP | disclosed |