Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PI4KA | P42356 | 2/20 | 0.77 |
| ▸ | PI4K2B | Q8TCG2 | 2/20 | 0.77 |
| ▸ | PI4K2A | Q9BTU6 | 2/20 | 0.77 |
| ▸ | PI4KB | Q9UBF8 | 2/20 | 0.77 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.53 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.51 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.51 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.51 |
| ▸ | SLC29A1 | Q99808 | 3/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.49 |
| ▸ | AMD1 | P17707 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | DPP4 | P27487 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | SLC28A1 | O00337 | 1/20 | 0.47 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30942645 | 1.00 | PI4KA (0.77) | PI4KAPI4K2BPI4K2API4KBALDH1A1 | |
| SCHEMBL12629188 | 1.00 | PI4KA (0.77) | PI4KAPI4K2BPI4K2API4KBALDH1A1 | |
| SCHEMBL1795588 | 1.00 | PI4KA (0.77) | PI4KAPI4K2BPI4K2API4KBALDH1A1 | |
| SCHEMBL66731 | 1.00 | PI4KA (0.77) | PI4KAPI4K2BPI4K2API4KBALDH1A1 | |
| SCHEMBL1757060 | 1.00 | PI4KA (0.77) | PI4KAPI4K2BPI4K2API4KBALDH1A1 | |
| SCHEMBL17568785 | 1.00 | PI4KA (0.77) | PI4KAPI4K2BPI4K2API4KBALDH1A1 | |
| SCHEMBL7735012 | 1.00 | PI4KA (0.77) | PI4KAPI4K2BPI4K2API4KBALDH1A1 | |
| SCHEMBL15395424 | 1.00 | PI4KA (0.77) | PI4KAPI4K2BPI4K2API4KBALDH1A1 | |
| SCHEMBL21882960 | 1.00 | PI4KA (0.77) | PI4KAPI4K2BPI4K2API4KBALDH1A1 | |
| SCHEMBL5672710 | 0.90 | PI4KA (0.63) | PI4KAPI4K2BPI4K2API4KBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11753432-B2 | Compound with analgesic effect for use in prevention and treatment of pain | ACADEMIA SINICA (TW) | 2023-09-12 | — | — | US | disclosed |
| EP-3573996-B1 | COMPOUND WITH ANALGESIC EFFECT FOR USE IN PREVENTION AND TREATMENT OF PAIN | ACADEMIA SINICA (TW) | 2022-06-15 | — | — | EP | disclosed |
| WO-2018140734-A1 | COMPOUND WITH ANALGESIC EFFECT FOR USE IN PREVENTION AND TREATMENT OF PAIN | ACADEMIA SINICA (TW) | 2018-08-02 | — | — | WO | disclosed |
| US-8129106-B2 | Sequence-specific detection of methylation in biomolecules | Max-Planck-Geselischaft zur Forderung der Wissenschaften E.V. (DE) | 2012-03-06 | — | — | US | disclosed |
| US-20110165564-A1 | SEQUENCE-SPECIFIC DETECTION OF METHYLATION IN BIOMOLECULES | MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2011-07-07 | — | — | US | disclosed |
| US-20080221060-A1 | Adenosine derivatives for treatment of pain and/or inflammation; diabetes | BIOVITRUM AB (PUBL) (SE) | 2008-09-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080221060-A1 | Adenosine derivatives for treatment of pain and/or inflammation; diabetes | ADORA3, ADORA2B, P2RX3 | PI4KA 2650/4885PI4K2B 2032/4885PI4K2A 2407/4885 |
| US-11753432-B2 | Compound with analgesic effect for use in prevention and treatment of pain | ADORA2B, ADORA1, ADORA3 | PI4KA 3007/4885PI4K2B 3300/4885PI4K2A 2830/4885 |
| US-20110165564-A1 | SEQUENCE-SPECIFIC DETECTION OF METHYLATION IN BIOMOLECULES | DNMT1, MAT2B, AHCY | PI4KA 4743/4885PI4K2B 4739/4885PI4K2A 4799/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.