SCHEMBL9105412

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL9889668	0.88	PLA2G7 (0.42)	ADAMTS4P2RX3HSD17B3FFAR1GRM5
	SCHEMBL9102397	0.86	PLA2G7 (0.34)	ADAMTS4P2RX3FFAR1GRM5
	SCHEMBL9105654	0.85	PLA2G7 (0.34)	ADAMTS4P2RX3GRM5
	SCHEMBL15275211	0.84	PLA2G7 (0.39)	HCAR2P2RX3
	SCHEMBL9889670	0.83	KDM4E (0.39)	P2RX3
	SCHEMBL9889514	0.82	HCAR2 (0.35)	HCAR2P2RX3
	SCHEMBL9107934	0.78	PLA2G7 (0.42)	HCAR2P2RX3RAB9ASMN1; SMN2
	SCHEMBL9892537	0.78	LMNA (0.43)	P2RX3FFAR1RAB9A
	SCHEMBL9889681	0.78	PLA2G7 (0.36)	HCAR2P2RX3RAB9ASMN1; SMN2
	SCHEMBL9101635	0.76	PLA2G7 (0.40)	HCAR2P2RX3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.