SCHEMBL9105602

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL16067917	0.88	NPC1 (0.50)	NPC1HTTACHEALDH1A1HPGD
	SCHEMBL10122755	0.84	TLR8 (0.39)	NPC1HTTHPGDKDM4ECYP2A6
	SCHEMBL27164750	0.83	BRD4 (0.43)	NPC1HTTACHEALDH1A1KDM4E
	SCHEMBL16807737	0.83	NQO1 (0.48)	ALDH1A1HPGDKDM4ENQO1CYP2A6
	SCHEMBL1355299	0.82	NPC1 (0.50)	NPC1HTTACHEALDH1A1HPGD
	SCHEMBL9108122	0.82	NQO1 (0.47)	NPC1HTTALDH1A1HPGDKDM4E
	SCHEMBL18382933	0.79	ALDH1A1 (0.45)	NPC1HTTALDH1A1HPGDKDM4E
	SCHEMBL28232454	0.79	NQO1 (0.60)	HTTALDH1A1HPGDKDM4ENQO1
	SCHEMBL24502998	0.79	AMY1A (0.45)	NPC1HTTACHEALDH1A1ACLY
	SCHEMBL21756115	0.78	ACHE (0.46)	NPC1HTTACHEALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.