Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | SLC2A1 | P11166 | 2/20 | 0.32 |
| ▸ | NNMT | P40261 | 1/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.32 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.32 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.32 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL667668 | 0.83 | ABCB1 (0.39) | POLBTDP1RAB9ANPC1MEN1 | |
| SCHEMBL9905363 | 0.79 | PLK1 (0.40) | POLBRAB9ANPC1MEN1KMT2A | |
| SCHEMBL5705240 | 0.77 | NPC1 (0.39) | RAB9ANPC1HPGDSMN1; SMN2HTT | |
| SCHEMBL18091876 | 0.73 | CTNNB1 (0.46) | RAB9ANPC1HPGDTSHRSMN1; SMN2 | |
| SCHEMBL17416601 | 0.70 | PLK1 (0.38) | RAB9ANPC1MEN1KMT2AHSD17B10 | |
| SCHEMBL9102042 | 0.70 | PLK1 (0.38) | RAB9ANPC1MEN1KMT2AHSD17B10 | |
| SCHEMBL9236827 | 0.69 | CTNNB1 (0.48) | POLBRAB9ANPC1MEN1KMT2A | |
| SCHEMBL20563025 | 0.68 | KDM4E (0.50) | POLBTDP1RAB9ANPC1MEN1 | |
| SCHEMBL9101301 | 0.67 | TP53 (0.43) | TDP1RAB9ANPC1MEN1KMT2A | |
| SCHEMBL14764988 | 0.66 | ABCB1 (0.34) | TDP1RAB9ANPC1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2463269-A1 | Bioavailable diacylhydrazine ligands for modulating the expression of exogenous genes via an ecdysone receptor complex | Intrexon Corporation (US) | 2012-06-13 | — | — | EP | disclosed |
| EP-2460786-A1 | Bioavailable diacylhydrazine ligands for modulating the expression of exogenous genes via an ecdysone receptor complex | Intrexon Corporation (US) | 2012-06-06 | — | — | EP | disclosed |