Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 8/20 | 0.56 |
| ▸ | ESR2 | Q92731 | 7/20 | 0.56 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.52 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | TYR | P14679 | 1/20 | 0.52 |
| ▸ | ESRRG | P62508 | 6/20 | 0.42 |
| ▸ | RXRA | P19793 | 2/20 | 0.42 |
| ▸ | RXRB | P28702 | 2/20 | 0.42 |
| ▸ | RXRG | P48443 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ESRRB | O95718 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | AR | P10275 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | HTR6 | P50406 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12733320 | 0.85 | LMNA (0.73) | ESR1ESR2LMNATYRESRRG | |
| SCHEMBL20472890 | 0.82 | GABRA1 (0.50) | GABRA1GABRB2LMNARXRARXRB | |
| SCHEMBL4057123 | 0.81 | CYP2C19 (0.50) | ESR1ESR2GABRA1GABRB2LMNA | |
| SCHEMBL29222655 | 0.80 | GABRA1 (0.48) | GABRA1GABRB2LMNARXRARXRB | |
| SCHEMBL28433211 | 0.80 | GABRA1 (0.48) | GABRA1GABRB2LMNARXRARXRB | |
| SCHEMBL9514169 | 0.79 | GABRA1 (0.52) | GABRA1GABRB2LMNATYRCYP3A4 | |
| SCHEMBL27273119 | 0.79 | CALM1 (0.52) | GABRA1GABRB2LMNARXRARXRB | |
| Hydroquinone SCHEMBL28201930 | 0.79 | TYR (0.61) | ESR1ESR2GABRA1GABRB2LMNA | |
| SCHEMBL292110 | 0.78 | ESR1 (0.54) | ESR1ESR2LMNATYRMEN1 | |
| SCHEMBL1121382 | 0.78 | ESR1 (0.82) | ESR1ESR2LMNATYRMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3658616-A1 | HALOGEN-FREE SULPHONIC ACID ESTER AND/OR SULPHINIC ACID ESTER AS FLAME RETARDANT, FLAME RETARDANT SYNERGISTS AND RADICAL GENERATORS IN PLASTICS | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. (DE) | 2020-06-03 | — | — | EP | claimed |
| CN-111393841-B | Preparation method of graphene nylon composite powder material for selective laser sintering | 湖南华曙高科技股份有限公司 | 2022-09-23 | — | — | CN | disclosed |
| CN-111393841-A | Preparation method of graphene nylon composite powder material for selective laser sintering | 湖南华曙高科技有限责任公司 | 2020-07-10 | — | — | CN | disclosed |
| EP-2471799-B1 | SAMARIUM COMPLEX AND USES THEREOF | NAT UNIV CORP NARA INST (JP) | 2015-04-15 | — | — | EP | disclosed |
| US-8975385-B2 | Rare-earth complex and uses thereof | National University Corporation NARA Institute of Science and Technology (JP) | 2015-03-10 | — | — | US | disclosed |
| EP-2471799-A1 | RARE-EARTH COMPLEX AND USES THEREOF | National University Corporation Nara Institute of Science and Technology (JP) | 2012-07-04 | — | — | EP | disclosed |
| US-20120140439-A1 | RARE-EARTH COMPLEX AND USES THEREOF | National University Corporation NARA Institute of Science and Technology (JP) | 2012-06-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120140439-A1 | RARE-EARTH COMPLEX AND USES THEREOF | LUC7L2, NDUFS5, NDUFS7 | ESR1 1131/4885ESR2 1106/4885GABRA1 2912/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.