Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 6/20 | 0.66 |
| ▸ | BCHE | P06276 | 2/20 | 0.44 |
| ▸ | FABP4 | P15090 | 1/20 | 0.42 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.42 |
| ▸ | HTR3A | P46098 | 6/20 | 0.40 |
| ▸ | HRH4 | Q9H3N8 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9105256 | 0.92 | ACHE (0.54) | ACHEFABP4FABP5HTR3AHRH4 | |
| SCHEMBL9105519 | 0.85 | ACHE (0.47) | ACHEBCHEALDH1A1KMT2AKDM1A | |
| SCHEMBL9107725 | 0.81 | ACHE (0.58) | ACHEBCHEFABP4FABP5HTR3A | |
| SCHEMBL9105665 | 0.81 | ACHE (0.62) | ACHEBCHEHTR3AKDM1A | |
| SCHEMBL9584001 | 0.80 | ACHE (1.00) | ACHEBCHEFABP4FABP5KMT2A | |
| SCHEMBL9109989 | 0.77 | KDM4E (0.39) | ACHEBCHEALDH1A1KMT2AKDM1A | |
| SCHEMBL9108831 | 0.75 | ACHE (0.60) | ACHEBCHEFABP4FABP5KDM1A | |
| SCHEMBL9109035 | 0.73 | ACHE (0.48) | ACHEFABP4FABP5HTR3AHRH4 | |
| SCHEMBL9106781 | 0.72 | BCHE (0.50) | ACHEBCHEALDH1A1KDM1A | |
| SCHEMBL9107842 | 0.71 | ACHE (1.00) | ACHEBCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4897400-A | ENHANCING MEMORY | HOESCHST-ROUSSEL PHARMACEUTICALS, INC. (US) | 1990-01-30 | — | — | US | claimed |
| US-5401749-A | Memory enhancers, cholinergic agents | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1995-03-28 | — | — | US | disclosed |
| US-4897400-A | ENHANCING MEMORY | HOESCHST-ROUSSEL PHARMACEUTICALS, INC. (US) | 1990-01-30 | — | — | US | disclosed |