Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 1/20 | 0.50 |
| ▸ | ACHE | P22303 | 1/20 | 0.50 |
| ▸ | KDM1A | O60341 | 3/20 | 0.44 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | NUDT1 | P36639 | 2/20 | 0.38 |
| ▸ | OGG1 | O15527 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | GPR3 | P46089 | 1/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9105665 | 0.91 | ACHE (0.62) | BCHEACHEKDM1APRKAA2ATM | |
| SCHEMBL9108871 | 0.83 | KDM1A (0.57) | BCHEACHEKDM1ATDP1L3MBTL1 | |
| SCHEMBL9352676 | 0.81 | KDM4E (0.50) | BCHEACHEKDM1APRKAA2TDP1 | |
| SCHEMBL9109989 | 0.81 | KDM4E (0.39) | BCHEACHEKDM1AL3MBTL1ALDH1A1 | |
| SCHEMBL9105256 | 0.80 | ACHE (0.54) | ACHEKDM1AALDH1A1CYP1A2 | |
| SCHEMBL9103472 | 0.80 | KMT2A (0.60) | BCHEACHEALDH1A1POLB | |
| SCHEMBL8781805 | 0.79 | ACHE (0.45) | ACHEKDM1AALDH1A1CYP1A2 | |
| SCHEMBL6464500 | 0.79 | BCHE (0.42) | BCHEACHEKDM1AL3MBTL1NUDT1 | |
| SCHEMBL9107151 | 0.76 | ACHE (0.82) | BCHEACHETDP1ALDH1A1CYP1A2 | |
| SCHEMBL9107670 | 0.75 | ACHE (0.61) | BCHEACHEKDM1AATMPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4897400-A | ENHANCING MEMORY | HOESCHST-ROUSSEL PHARMACEUTICALS, INC. (US) | 1990-01-30 | — | — | US | claimed |
| US-5401749-A | Memory enhancers, cholinergic agents | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1995-03-28 | — | — | US | disclosed |
| US-4897400-A | ENHANCING MEMORY | HOESCHST-ROUSSEL PHARMACEUTICALS, INC. (US) | 1990-01-30 | — | — | US | disclosed |