Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 2/20 | 0.54 |
| ▸ | FABP4 | P15090 | 1/20 | 0.46 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.46 |
| ▸ | HTR3A | P46098 | 6/20 | 0.42 |
| ▸ | HRH4 | Q9H3N8 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | KDM1A | O60341 | 1/20 | 0.36 |
| ▸ | MPO | P05164 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9106547 | 0.92 | ACHE (0.66) | ACHEFABP4FABP5HTR3AHRH4 | |
| SCHEMBL9109989 | 0.84 | KDM4E (0.39) | ACHEALDH1A1KDM1A | |
| SCHEMBL9109035 | 0.80 | ACHE (0.48) | ACHEFABP4FABP5HTR3AHRH4 | |
| SCHEMBL9106781 | 0.80 | BCHE (0.50) | ACHEALDH1A1KDM1ACYP1A2 | |
| SCHEMBL9355887 | 0.77 | NPC1 (0.46) | ACHEALDH1A1KDM1ATSHR | |
| SCHEMBL9105519 | 0.77 | ACHE (0.47) | ACHEALDH1A1KDM1A | |
| SCHEMBL9106918 | 0.74 | ACHE (0.55) | ACHEFABP4FABP5KDM1A | |
| SCHEMBL10847217 | 0.73 | CYP1A2 (0.47) | ACHEALDH1A1CYP1A2TSHR | |
| SCHEMBL9107725 | 0.73 | ACHE (0.58) | ACHEFABP4FABP5HTR3AHRH4 | |
| SCHEMBL9105665 | 0.71 | ACHE (0.62) | ACHEHTR3AKDM1ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4897400-A | ENHANCING MEMORY | HOESCHST-ROUSSEL PHARMACEUTICALS, INC. (US) | 1990-01-30 | — | — | US | claimed |
| US-5401749-A | Memory enhancers, cholinergic agents | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1995-03-28 | — | — | US | disclosed |
| US-4897400-A | ENHANCING MEMORY | HOESCHST-ROUSSEL PHARMACEUTICALS, INC. (US) | 1990-01-30 | — | — | US | disclosed |